A direct meta-lithiation route to 1,3-disubstituted ferrocenes
Christophe Pichon,Barbara Odell,John M. Brown
Chemical Communications Pub Date : 02/10/2004 00:00:00 , DOI:10.1039/B314641C
Abstract
Ferrocenyl sulfides afford meta-lithiation products with up to 94% regioselectivity on reaction with s-BuLi; the resulting 1,3-disubstituted ferrocenes can then be reacted with a variety of electrophiles.
