Catalytic asymmetric synthesis of 1,3-enyne scaffolds: design and synthesis of conjugated nitro dienynes as novel Michael acceptors and development of a new synthetic methodology†,10.1039/C3CC48951E

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Catalytic asymmetric synthesis of 1,3-enyne scaffolds: design and synthesis of conjugated nitro dienynes as novel Michael acceptors and development of a new synthetic methodology†

Xiang Li,Fangzhi Peng,Mingtao Zhou,Mingjie Mo,Ruirui Zhao,Zhihui Shao

Chemical Communications Pub Date : 12/16/2013 00:00:00 , DOI:10.1039/C3CC48951E

Abstract

A novel catalytic enantioselective synthesis of functionalized 1,3-enynes has been developed featuring the design and synthesis of conjugated nitro dienynes as a useful new class of Michael acceptors. Moreover, a simple, yet flexible catalytic cascade approach to functionalized enantioenriched acyclic α,β-enones and cyclic dienones has also been developed.