Catalyst-free microwave-assisted arylglyoxal-based multicomponent reactions for the synthesis of fused pyrans†
Richa Mishra,Lokman H. Choudhury
RSC Advances Pub Date : 03/03/2016 00:00:00 , DOI:10.1039/C5RA25536H
Abstract

A series of functionalized pyrans fused with quinolones, naphthoquinones, coumarins and pyrones have been synthesized using three component reactions of arylglyoxal monohydrate, malononitrile, and a wide range of cyclic 1,3-dicarbonyls under microwave irradiation. This method is a simple and straightforward method for the easy access of fused and functionalized pyrans tethered with an aroyl group without involving any catalyst and column chromatographic purifications.

Graphical abstract: Catalyst-free microwave-assisted arylglyoxal-based multicomponent reactions for the synthesis of fused pyrans