Chiral sulfur derivatives in the allylation of acyl hydrazones: C2-symmetric bis-sulfinamides as enhanced chiral organic promoters.†
Inmaculada Fernández,Ana Alcudia,Beatrice Gori,Victoria Valdivia,Rocío Recio,María Victoria García,Noureddine Khiar
Organic & Biomolecular Chemistry Pub Date : 08/06/2010 00:00:00 , DOI:10.1039/C0OB00078G
Abstract

Monosulfinamides and C2-symmetric bis-sulfinamides are convenient neutral chiral promoters in the allylation of acyl hydrazones, the nature of the spacer and the substituent at the sulfinyl sulfur are key elements for the enantioselectivity of the process.

Graphical abstract: Chiral sulfur derivatives in the allylation of acyl hydrazones: C2-symmetric bis-sulfinamides as enhanced chiral organic promoters.