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Catalytic intramolecular carbonyl–ene reaction with ketones: evidence for a retro–ene process†
P. Tremel,C. Iacobucci,L. Massi,S. Olivero,J.-F. Gal,E. Duñach
New Journal of Chemistry Pub Date : 07/23/2015 00:00:00 , DOI:10.1039/C5NJ01286D
Abstract

The ene-process with unsaturated ketones was catalyzed by Lewis acids such as bismuth or indium triflates. Unlike aldehydes, the reverse ene-process occurs with ketones, resulting in incomplete conversions, as shown by control experiments and analysis by ESI-MS.

Graphical abstract: Catalytic intramolecular carbonyl–ene reaction with ketones: evidence for a retro–ene process
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