A fast and oxygen-promoted protocol for the ligand-free Suzuki reaction of 2-halogenated pyridines in aqueous media†
Chun Liu,Weibo Yang
Chemical Communications Pub Date : 09/03/2009 00:00:00 , DOI:10.1039/B912364D
Abstract
A fast protocol has been developed for the construction of 2-aryl-substituted pyridine derivatives by the oxygen-promoted, ligand-free, Pd(OAc)2-catalyzed Suzuki reaction of 2-halogenated pyridines in aqueous isopropanol.