A distinct novel approach for the synthesis of 3-indolyl-methanamines starting from indoles, aldehydes and nitrobenzenes in water†‡,10.1039/C3RA41131A

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

A distinct novel approach for the synthesis of 3-indolyl-methanamines starting from indoles, aldehydes and nitrobenzenes in water†‡

Biswanath Das,Jayprakash Narayan Kumar,Avula Satya Kumar,Gandham Satyalakshmi,Digambar Balaji Shinde

RSC Advances Pub Date : 07/01/2013 00:00:00 , DOI:10.1039/C3RA41131A

Abstract

3-Indolyl-methanamines have efficiently been synthesized by the treatment of indoles with aldehydes and nitrobenzenes using indium in aqueous HCl at room temperature. The products are formed in excellent yields (91–98%) within a short period of time (30–45 min). Bisindolyl methanes have not been obtained under the present reaction conditions.