Chiral spiro iridium catalysts with SpiroPAP ligands: highly efficient for asymmetric hydrogenation of ketones and ketoesters
Xiao-Hui Yang,Jian-Hua Xie,Qi-Lin Zhou
Organic Chemistry Frontiers Pub Date : 01/16/2014 00:00:00 , DOI:10.1039/C3QO00056G
Abstract
This tutorial account describes the design of chiral spiro iridium catalysts bearing spiro pyridine–aminophosphine ligands, and their preparation and application in the asymmetric hydrogenation of ketones and β-aryl-β-ketoesters.
