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Comparing dendritic with linear esterase peptides by screening SPOT arrays for catalysis†‡
Rasomoy Biswas,Noélie Maillard,Jacob Kofoed,Jean-Louis Reymond
Chemical Communications Pub Date : 10/21/2010 00:00:00 , DOI:10.1039/C0CC02700F
Abstract

Fluorescence screening of a 96-membered SPOT library of histidine containing dendritic and linear peptides revealed the remarkable esterolytic activity of short histidine oligomers that show catalytic proficiencies within one order of magnitude of histidine-containing esterase peptide dendrimers.

Graphical abstract: Comparing dendritic with linear esterase peptides by screening SPOT arrays for catalysis
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