The epoxidation of 6β-acetoxyandrosta-2,4-diene-17-one, 6β-acetoxypregna-2,4-diene-20-one and the corresponding 6-ketones with m-chloroperbenzoic acid is shown to give, unexpectedly, the 4α,5α-monoepoxides.

Pyrazolo[3,4-b][1,6]naphthyridine, pyrazolo[3,4-b]pyridine and pyrazolo[3,4:2,3]pyrido[6,1-a]benzimidazole derivatives are synthesized starting from the isomeric 3-substituted 5-chloro-1-phenylpyrazole-4-carbaldehyde.

The new photosensitizers, monomethine, dimethine, trimethine, styryl and mixed cyanine dyes incorporating pyrazolo/oxazole(thiazole) nuclei are prepared; the visible absorption spectra for all the synthesized cyanines were examined in 95% ethanol; structural confirmation is carried out by elemental analysis, IR and 1H NMR spectroscopy.

2-Aryl-1,2,3,4-tetrahydro-4-quinolones are converted in high yields to the corresponding 2-aryl-4-methoxyquinolines using molecular iodine in refluxing methanol; the structures of the quinoline derivatives are determined using 1H and 13C NMR spectroscopic techniques.

Several symmetrically disubstituted ureas and thioureas are synthesized by heating of urea or thiourea with aromatic amines or phenylhydrazine under environmentally benign conditions without any solvent in a conventional microwave oven.

The synthesis of a (Te,S) ligand 4-MeOC6H4TeCH2CH2SEt (L) and its complex [PdCl2L] is followed by single crystal structure determination of the complex, which indicates that the Pd–Cl bond length trans to the ArTe group [2.344(3) Å] is longer than that trans to SEt [2.316(4) Å], suggesting a stronger trans influence for the former.

The 1,3-dipolar activity of hydrazonoyl chlorides and oxime chlorides over alumina with various alkenes and alkynes under microwave irradiation is studied; a comparative study between dry media conditions and the procedure in homogeneous solution under microwave and classical heating is described.

Allylsamarium bromide reacts with nitroalkenes to give conjugate addition compounds in moderate to good yields.

The syntheses of a C-4:C-6 furano-steroid by the base-catalysed cyclization of 6α-acetoxyandrost-4-ene-3,17-dione and of a C-4:C-6 tetrahydrofuran by the cyclization of 3β,6β-dihydroxy-4β-hydroxymethylandrostan-17-one, are described.

The title hydroxylamine in sodium dodecyl sulfate micelles containing benzophenone is subjected to photorearrangements giving benzoyloxy- and phenyl-migrated products along with fragmentation products; subsequent photohydrolysis of the 1,5-benzoyloxy-rearranged product proceeds selectively.

Reactions of 4-hydroxycoumarin and 4-hydroxyfurocoumarins with αβ-unsaturated nitriles provide routes to a range of novel pyranocoumarins and furopyranocoumarins, respectively.

Azoloazines are produced via the reaction of aminoazoles with enaminones, enaminonitriles and ethyl alkylidene cyanoacetate.

Promoted by gallium triiodide, an α-bromoketone, bromomethyl phenyl ketone, is treated with acyl chlorides to synthesize 1,3-diketones in good yields under mild and neutral conditions.

Gaseous N2O4 reacts with 18-crown-6 to afford a stable ionic complex of NO+·18-crown-6·H(NO3)2–; this complex is an efficient nitrosating agent for the conversion of thiols to their corresponding S-nitrosothiols in different organic solvents.

The mixed-metal mixed-halide complex [CuPbBrIL2]2 has been prepared by the direct interaction of zerovalent copper with lead halides and 2-dimethylaminoethanol (HL) in dmso and has been characterized by X-ray crystallography; the structure shows a layer arrangement of the tetranuclear metal units through the µ3-halogen bridging.

The preparation of Ph3P(SCN)2 is modified by using a combination of Ph3P, NH4SCN and Br2 at room temperature for the efficient conversion of primary, secondary and tertiary alcohols to their corresponding thiocyanates in excellent yields.

A convenient one-pot synthesis of pyrimido[4,5-b]quinolines as non-classical 5-deaza antifolate inhibitors by the reaction of 6-amino-4-oxo-2-thioxotetrahydropyrimidine 1 with aromatic aldehydes and dimedone is reported.

The thermal cycloaddition of azido sugar 3 with C60 gives the chiral azafulleroid 4 in 2.55% yield (8% based in recovered C60).

N-phosphoamino acids with long dialkoxy chains are synthesized and spectral data given.

Warming a title acid with SOCl2 gives the corresponding 3,3,9-trichlorothieno[3,4-b]quinolin-1(3H)-one whereas reaction at room temperature leads to the intermediate 3,3-dichloro-4-ethylthieno[3,4-b]quinoline-1(3H),9(4H)-dione product as established from the respective X-ray crystallographic determinations.