The migration and retention of deuterium which occurs during aromatic hydroxylation of several substrates (NIH Shift) with a range of fungi is compared to the migration and retention obtained with liver microsomes and a chemical model system; enzymatic mechanisms are discussed in terms of arene oxide intermediates.

Treatment of methyltitanium trichloride with tetraethylammonium chloride or tetraethylammonium bromide yields three series of anions (depending on the mole ratios used), two of which are binuclear.

The second-order rate constants for the racemisation of 4-isobutyl-2-phenyl-L-oxazoline-5-one by triethylamine and di-isopropylethylamine in chloroform at 25° were 1400 1 mol–1 min–1 and 113 l mol–1, min–1, respectively.

An unstable binuclear titanium complex with molecular nitrogen has been isolated at low temperatures and its composition has been determined; the complex is an intermediate in the reduction of dinitrogen to hydrazine and ammonia.

The dihydroalumination of hex-1-en-5-yne in diethyl ether or triethylamine affords 2,α-bis-aluminomethylcyclopentane and 2,α-bis-alumino-3-methylcyclopentene derivatives, respectively.

The preparation and characterization of several series of mixed ligand cobalt(I) complexes of the types [Co(CN)2(CO)2(PR3)]–, [Co(CN)2(CO)(PR3)2]–, and [Co(CN)(CO)2(PR3)2], prepared by the reactions of tertiary phosphines (PR3) with [Co(CN)3(CO)2]2–, are described and some novel aspects of their chemistry are discussed.

X-Ray structure analysis of Pt(PPh3)2(C3H4) shows that, unlike in other transition-metal–allene complexes in which allene is perpendicular to the co-ordination plane, allene is in the co-ordination plane.

On the enzyme isopentenyl phyrophosphate isomerase, a proton is added to the re side of the double bond of 3-methyl-3-butenyl pyrophosphate.

High-resolution 15N n.m.r. spectra of a series of amino-acid methyl esters as their hydrochlorides have been measured in natural abundance and reveal the presence of a γ-alkyl substituent effect, similar to that observed in 13C n.m.r.

The use of α-deuteriated substrates has established that in the lead tetra-acetate oxidation of certain secondary alicyclic and open-chain alcohols, ketone formation proceeds, in part, by 1,4-transfer of hydrogen from the carbinol (α) carbon atom to the δ-carbon atom.

The synthesis and properties of air-stable hydroborato-complexes, trans-[MA(CO)(R3P)2][M = Ir, Rh; A = BH3(CN), BH4; R3P = tertiary phosphine] are reported; the co-ordination of BH3(CN)–, probably through the –NC group, is the first example of this anion acting as a ligand.

Ring opening of exo,exo and exo,endo-1,3-diethyl-2,4-dimethoxycarbonylbicyclobutane at 300–400 °C and 1–3 s reaction time follows the Woodward–Hoffman rules.

A deprotonated ethylenediamine ruthenium complex, previously reported to be an RuVI–amide system, has been shown by X-ray photoelectron spectroscopy in conjunction with its diamagnetism, to be a ruthenium(II) complex, and shown by n.m.r. spectroscopy to contain an α-di-imine chelate ring.

The reaction of an alkyl or aryl disulphide with silver(I) ion and alkyl or aryl amines gives good yields of the corresponding sulphenamides.

Some key features of the mass spectral fragmentation patterns of aminocyclitol antibiotics are discussed.

Clerodendrin A, the bitter principle and antifeeding repellent, is shown to be a diterpene of clerodon skeleton with the structure (I).

A ground-state interactions, which shows a dependence on conformation leads to the splitting of the degenerate πCC orbitals in the ketone (2).

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The structure of the unusual complex [Ni-(Sbtas)2](ClO4)2[Sbtas = tris-(o-dimethylarsinophenyl)stibine] is essentially square-pyramidal involving the [Ni(Sb2As3)]2+ donor set.