A new method using substituted 8-aminoquinoline as a directing group has been developed for chlorotrifluoromethylation of unactivated alkenes. 4-Pentenamide substrates show high efficiency with yields up to 99 % under mild conditions. With a broad substrate scope, the reaction can be scaled up to the gram scale and has potential for applications in the pharmaceutical industry.

For two complex aluminium hydrides, the quadrupole coupling parameters of the 27Al nuclei are determined from static NMR spectra and compared with those obtained from MAS NMR spectra and from DFT-GIPAW calculations based on structural data from diffraction methods.

A novel and eco-friendly method for preparing Fe3O4@Ag and α-Fe2O3@Ag core-shell with high magnetism and potent cytotoxic activity is detailed. The Fe3O4@Ag and α-Fe2O3@Ag core-shell NPs were produced using S. persica bark extract. AN MTT assay demonstrated the potent cytotoxic activity of the synthesized core-shell against breast cancer (MCF-7) and human umbilical vein endothelial (HUVEC) cells. These nanoparticles were capable of displaying a high potential cytotoxic performance against cancer cell line.

Heterogeneous catalysts were prepared and tested in the hydrogenation of CO2 to methanol. These are based on the concept of precapture and transformation used in homogeneous systems.

Copper oxide nanoparticles were covalently functionalized with specific Gram-positive and Gram-negative antibodies for targeted and differential antibacterial activity.

Twisted or helical shape 1,2-position-connected terazulene and quaterazulene were synthesized. Variable temperature NMR measurements and theoretical calculations of the quaterazulene suggest that the syn-type structure with terminal azulene overlap is more stable. Planar or bent shape fused terazulenes were also synthesized. Nucleus-independent chemical shift (NICS) calculations carried out for the central seven-membered ring of the bent shape fused terazulene showed a positive value, suggesting anti-aromatic properties.

The application of porous materials in atmospheric water harvesting is summarized from the aspects of variety, static performance, kinetic performance, devices, and more., and the prospect of its future development is put forward.

Computational modeling of xanthine-based inhibitors binding to the allosteric site of MTHFD2, with promising anticancer activity, was carried out. Using docking/IFD, MD simulations and binding free energy calculations, the binding modes in the MTHFD2 and MTHFD1 allosteric sites were analyzed, establishing a clear correlation with biological activity and selectivity. MD trajectories were furthermore analyzed to verify reported conformational changes in MTHFD2.

An open liquid plasticine-based FASS system (FASS: field-amplified sample stacking) for protein enrichment was developed, with which proteins can be enriched 40–80-fold by LP-FASS within 40 min.

An efficient approach to annelated tetra(hexa)azacyclopenta[a]anthracenes, tetraazaindeno[5,4-b]fluorenes, and oxatetraazacyclopenta[m]tetraphene was accomplished via the one pot three-component reaction involving 7-amino-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-5-one with aromatic aldehydes and the corresponding active 1,3-dicarbonyl compounds (namely, dimedone, 1,3-dimethylbarbituric acid, 1,3-indanedione, and 4-hydroxycoumarine)

The high thermoelectric figure-of-merit (zT) of 1.4 reported in (Yb0.9Mg0.1)Cd1.6−xMg0.4ZnxSb2 (x=0.4) is explained in terms of its physical reason. Although the weighted mobility of x=0.4 is the lowest among other Zn alloying content (x), because the lattice thermal conductivity at x=0.4 is also the lowest, the corresponding quality factor becomes the highest with the maximum zT.

The tin bromido aluminates [Sn3(AlBr4)6](Al2Br6), Sn(AlBr4)2, [EMIm][Sn(AlBr4)3] and [BMPyr][Sn(AlBr4)3] are prepared in ionic liquids. Some exhibit 3D network structures and bright Sn2+-based photoluminescence with quantum yields near 100 %.

KCl release from a hydrogel consisting of poly(vinyl alcohol), Premna Oblongifolia Merr. extract, glutaraldehyde and carbon nanotubes as well as KCl (VOGmC7-KCl) was started by catastrophic dissolution of KCl from the hydrogel surface, followed by surface cleansing, and ended with desorption of KCl from inside the hydrogel following zeroth-order kinetics with k=1.2645×10−3 mg/s. Together with other measured characteristics, this kinetics profile demonstrates that VOGmC7 hydrogels are promising candidates for developing controlled-release fertilizers.

Indolines or dihydroindoles play a key role in drug discovery, and many drugs containing indoline cores have been reported recent years. We focus on indoline compounds in development, synthesis and use as anticancer drugs, antibacterial drugs etc. in recent years. Through the analysis of the indolines’ interaction with proteins and highlighting the advantages of its properties in drug design, this review aims to provide a toolbox for readers to design and discover new drugs.

The complete conversion technology of biomass developed in this paper transforms all the three components of solid biomass into fluids, not only obtaining the desired yield of small molecules, but also providing a favorable raw material for the subsequent upgrading, promoting heat and mass transfer, and facile separation of catalyst.

ML to the help for SERS: Applications of Surface-Enhanced Raman Spectroscopy (SERS) combined with Machine Learning (ML) in recent years are summarized in this review, including the recognition of biological molecules, rapid diagnosis of diseases, developing of new immunoassay techniques, and enhancing SERS capabilities in semi-quantitative measurements.

3,4-Dimethylpyridine strengthening copper(II): Three copper(II) complexes of 2-[(2,4-dihydroxyphenyl)methylidene]-N-(prop-2-en-1-yl)hydrazine-1-carbothioamide and N-heteroaromatic bases were synthesized and studied by elemental analysis, FTIR spectroscopy and single crystal X-ray crystallography. The study of antimicrobial, antifungal and antioxidant activities showed that the most active one is the copper(II) complex with 3,4-dimethylpyridine in the inner sphere.

Ga1-xSnxPd2 is a platform material in the semi-hydrogenation of acetylene. Its catalytic activity is analyzed from the point of view of chemical bonding. Pronounced charge transfer from the p elements to palladium results in the formation of the negatively charged catalytic centers. Combination of all features of the chemical bonding and electronic structure yield the peak of catalytic activity at x ≈ 0.25.

Thermal response measurements as well as volumetric water physisorption measurements are applied to study the influence of particle sizes on water adsorption capacity and kinetics. For this, a controlled thermal condensation process followed by a mechanical treatment using a ball mill is applied to synthesize C2N-type carbon materials with smaller and larger particle sizes. The nitrogen-rich surfaces and narrow distributed micropores endow them with remarkable hydrophilic features. Using the InfraSORP technique, a fast and accurate assessment of these properties is demonstrated.

Lead coating: The crystal structures of both N-(thiomorpholine-4-carbothioyl)benzamide ligand and bis(N-(thiomorpholine-4-carbothioyl)benzamidate)lead(II) complex are reported, and the usability of the complex as a single-source molecular precursor for the deposition of PbS thin films via spin coating is demonstrated. The films show a blue shift in their absorption behavior and consist of particles with cuboidal morphology.