Supramolecular nanocarriers entitled TSCD/MCC NPs have been designed and prepared based on the electrostatic interaction between heptakis-substituted thiosulfate-β-cyclodextrins (TSCD) and myristoyl choline chloride (MCC). TSCD/MCC NPs featuring pH/AChE co-response properties are employed to load, deliver, and release the antitumor compound Triptolide (TPL).

NHC-Au(I)-thiolato complexes, as analogues of the potent HIF-1α inhibitor AC1-004, showed enhanced anti-angiogenic effects and low micromolecular IC50 values in cytotoxicity tests against human cancer cell lines, depending on their residues R1 and R2. Their pleiotropic mode of action was investigated.

InCl-EtioP-I was synthesized and comprehensively characterized both analytically and theoretically. Thin films of InCl-EtioP−I were obtained by thermal evaporation in vacuum and their photoelectrical parameters were estimated. A very high photo-to-dark current ratio of ∼106 was detected in simple single-layer devices. Single crystal X-ray analysis reveals a unique molecule packing resulting in a 2D double layered structure.

In this mini-review, we discuss and summarize the recent progress of carbon-electrode materials and their applications in the field of organic photovoltaics, particularly how they work as alternatives to conventional TCO and metal electrodes. We expect this mini-review will inspire more research efforts to develop high-performance OSC-matched carbon materials for more efficient and stable carbon-electrode-based organic solar devices.

A two-step procedure for the degradation of Polyvinyl chloride (PVC) is demonstrated. Elimination of HCl using base affords double bonds on the polymer backbone, which are then cleaved by olefin metathesis with an added alkene. The molecular weight of the products is greatly reduced from the original PVC, and a diene corresponding to the added alkene is obtained. This provides an initial proof of concept towards upcycling PVC into new chemical products.

New products of photo- and thermal rearrangements of 19-membered azoxybenzocrown with two phenyl substituents in benzene rings are characterized. The structures of new hydroxyazobenzocrowns and also the atypical product of rearrangements was confirmed by X-ray diffraction analysis in the solid state. Tautomeric equilibrium of hydroxyazobenzocrowns was investigated. The rearrangement course and properties were compared with the previously obtained 19-membered analogs.

The co-pyrolysis of LDPE and PS waste plastic is discussed in this work, with the aim to improve the overall yield to high value BTX (benzene, toluene, xylenes) chemicals which support the processing of plastics that generally appear in mixtures. This work features actual reactor performance product profile that was validated with in-situ FTIR of mixed plastic catalytic co-pyrolysis.

Intramolecular cyclization of alkynes possessing endogenous carbon nucleophiles by homogeneous gold catalysis with emphasis on exo- vs endo- regioselectivity was overviewed. Perspective of regiochemical parameters contributing for such selectivity for individual reactions was discussed. Application of regioselective carbocyclization in natural product synthesis and π-functional materials is highlighted in selective cases.

Fresh air and clean water are essential constituents for the human population as well as for fauna and flora to bloom. Owing to the extreme toxicity of NACs and VOCs in physiological systems and their widespread presence in the environment, a serious concern is required. The innovation of chemosensors for these two types of harmful organic contaminants (NACs i.e., nitroaromatics, and VOCs i.e., volatile organic compounds) have unfolded as a key research topic in recent decades, garnering a lot of attention due to their environmental, industrial and biological importance. In recent years, there has been a significant amount of research on both NACs and VOCs chemosensors. This review article has recapitulated the latest development of fluorescent chemosensors especially small molecular frameworks from 2015 to 2022, for NACs and VOCs which has been discussed individually. In addition, the detection of NACs and VOCs on multiple platforms with a special focus on their mechanistic exploration, as well as their probable applications in natural water body specimens, vapor phase detection, and paper strip analysis have also been discussed, in this review.

Unlocking the potential of phosphino hydrazones: Harnessing the power of hydrazone condensation to synthesise phosphino hydrazone ligands from 3-(diphenylphosphino)propanal and commercially available aryl hydrazines and studying their palladium complexes for Cu-free Sonogashira cross-coupling reaction.

The recognition of carbohydrate plays a key role in numerous biological processes. Thus, artificial receptors have been synthesized to mimic these biological systems. To date, most of the receptors reported for carbohydrate complexation present highly symmetrical cavities, probably because their syntheses require less synthetic efforts and are easier to achieve and control. However, carbohydrates display complex, asymmetrical structures suggesting that hosts with low symmetry might be more adapted to recognize these guests. Here, we described the strategies that have been used to complex carbohydrates with macrocycles and cages presenting low symmetry and the potential of this approach. Self-assembled cages are first described, then covalent macrocycles and cages are presented and for each example the binding properties of low-symmetry systems are compared to those of their higher-symmetry counterparts.

Mechanochromic polymers can be fabricated by physically doping into or covalently bonding mechanophores to selected polymer matrices, enabling mechano-responsive allochroic and mechanoluminescent behaviors. These materials have shown potential applications in bionic actuators, encryption, signal sensing, and beyond.

An analysis of Raman and Raman optical activity (ROA) spectra of glutathione based on computational modeling revealed that this peptide is flexible, but its conformation profile does not change significantly across a wide pH range. The adopted methodology could be appropriate for further structural studies of similar biomolecular systems.

The first near IR fluorescent probe for the chemoselective and enantioselective recognition of arginine in aqueous solution is reported in this work. This probe also allows visual discrimination of the arginine enantiomers because of its fast and distinct color change upon interaction with the substrate.

A series of pseudorotaxanes with supramolecular organometallic silver(I) and gold(I) pillarplexes acting as rings and different α,ω-dicarboxylic acids as axle components are reported. The successful formation of the host-guest complexes is shown by 1H NMR spectroscopy and respective NMR titration. Additional evaluation with ITC titration experiments yielded dissociation constants (Kd) ranging from 10-5 to 10-7 M. Single-crystal X-Ray diffraction analysis reveals a particularly exciting pore alignment of different examples in the solid state depending on the length of the guest. The work highlights, that dicarboxylic acids can penetrate the tight tubular pillarplex pore, paving the way to future mechanically interlocked molecules and materials.

We have analyzed the nature and role of functional groups on the self-assembly modes and the physical properties of multicomponent gels with structurally similar individual components. The gelation properties of individual and mixed enantiomeric compounds of biphenyl bis-(amides) of alanine (BPA) or phenylalanine (BPP) methyl ester were analyzed in various solvent/solvent mixtures. Multicomponent gels were formed by mixing the enantiomeric BPP compounds at a lower concentration, but a higher concentration was required for mixed alanine-based BPA gels. The comparison of the mechanical strength of the individual and mixed BPP compounds indicated that the mixed BPP gels displayed enhanced mechanical strength (~2-fold increase) in p-xylene, but a weaker gel was observed in DMSO/water. However, a reverse trend was observed for BPA gels, indicating the role of functional groups in the gel network formation. X-ray diffraction analysis of the gelator and the xerogels in the solid state confirmed the formation of co-assembled networks in mixed enantiomeric gels. The stability of the gels towards anions was evaluated by analyzing the anion induced stimuli-responsive properties. These results indicate the effective modeling of the functional groups of the individual components could lead to multicomponent gels with tunable properties.

Hybrid ligands (L) combining trioxaphosphaadamantane and nitrile donor groups at the different backbones (ferrocene-1,1′-diyl and 1,2-phenylene) were used to prepare dimeric complexes [Au2{μ(P,N)-L}2][SbF6]2, which are applicable as well-defined and stable yet highly catalytically active, silver-free Au(I) homogeneous catalysts.

Aurophilic, OH⋅⋅⋅N hydrogen bonding and π-π interactions governed the supramolecular assemblies in the solid state of two new dicyanoaurate(I)-based Mn(II) complexes with auxiliary bis-pyridine ligands

The reaction to obtain furan alcohols is one of the most important in the upgrading of furan derivates. An attractive route is the transfer hydrogenation of furfural using acidic-basic catalysts. In this work, mixed oxides derived from ternary hydrotalcites were employed to obtain furfuryl alcohol from furfural assisted by microwave irradiation. The reaction was studied using containing Co2+ and Ni2+ in their structure and was then optimized using distinct primary and secondary alcohols as hydrogen donor sources, as well as distinct temperatures and initial concentrations of furfural. The yields to furfuryl alcohol are strongly dependent on the type of Me2+ in layered oxides mainly due to higher basicity and also to the donor employed in the reaction. The mixed oxide containing Co2+ showed complete conversion of furfural and higher yields to furfuryl alcohol (> 95%) at short times of reaction (< 1 h).

Hydrogen evolution reaction (HER) coupled with biomass conversion is a sustainable route to produce clean energy H2 and value-added chemicals simultaneously. Herein, an amorphous Ni-Mo-B-O bifunctional electrocatalyst was synthesized through a facile electrodeposition method and employed as a cathode for HER to produce H2 and as an anode for the conversion of hydroxymethylfurfural (HMF) to furandicarboxylic acid (FDCA). Besides leading to the formation of amorphous structures, the introduction of Mo and B can increase the electron density and optimize the electronic structure of the electrocatalyst, thus substantially increasing the catalytic activity of the catalyst. After continuous reaction at a constant potential of 0.58 V vs. Hg/HgO for 8 hours, the conversion of HMF reached 98.86%, and the selectivity of the target product FDCA was as high as 92.97%. Finally, a two-electrolyzer system was constructed using the amorphous Ni-Mo-B-O as both cathode and anode to achieve simultaneous H2 production in the cathode chamber and FDCA production in the anode chamber at a low voltage. This work presents a promising strategy for the design and synthesis of high-performance non-noble metal electrocatalysts for efficient and cost-effective H2 production.