960化工网
钾离子通道化合物库

钾离子通道是分布最广泛的离子通道,几乎存在于所有生物体中。钾离子通道主要有四类:电压门控钾离子通道(voltage-gated potassium channel)、钙激活钾离子通道(calcium-activated potassium channel)、内整流钾离子通道(inwardly rectifying potassium channel)和串联孔域钾离子通道(tandem pore domain potassium channel)。越来越多的研究表明钾通道功能障碍与多种疾病相关,如慢性高血压、糖尿病、高胆固醇血症和动脉粥样硬化等。

Chem960钾离子通道化合物库包含钾离子通道抑制剂化合物,是进行心血管疾病药物开发及钾离子通道研究的有用工具。


钾离子通道化合物库 详情
活性描述 & 特点

•   A unique collection of 165 potassium channel inhibitors and activators for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of cardiovascular diseases drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

化合物库组成

上海源叶生物科技有限公司
VIP会员

平台客服
平台客服
平台在线客服