免疫系统是一个宿主防御系统,由机体内的许多生物结构和进程组成,用以防御疾病。为了机体的正常工作,免疫系统必须检测到各种各样的病原体,从病毒到寄生虫,并将它们与机体自身的健康组织区分开来。炎症也是身体自我保护的尝试,以消除有害的刺激,并开始愈合的过程。炎症反应是身体免疫反应的一部分。免疫系统识别受损细胞、刺激物和病原体,炎症开始愈合过程。炎症反应失调是机体的一大类疾病,它是人类多种疾病的基础。免疫系统与炎症反应失调有关,表现为过敏反应和某些肌病,许多免疫系统紊乱导致异常炎症。
Chem960 收录了免疫炎症相关小分子抑制剂化合物,可以用于免疫炎症研究及自身免疫炎症疾病的药物开发。
• A unique collection of 902 small molecules with biological activity used for Immunology/Inflammation research.
• The library contains compounds targeting Immunology/Inflammation-related enzyme such as CCR, COX, Interleukin Related, IRAK, MyD88, PDE, PD-1/PD-L1, TLR, and more.
• A useful tool for researching the mechanism behind Immunology/Inflammation, drug screening and other pharmaceutical and biological applications.
• Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.
• Structurally diverse, medicinally active, and cell permeable.
• Rich documentation with structure, IC50, and brief introduction.
• NMR and HPLC validated to ensure high purity and quality.
• All compounds are in stock and continuously updated.