膜蛋白是附着在细胞膜或细胞器上的蛋白质分子。 膜蛋白可根据其与膜的结合方式分为两类:整合膜蛋白（也称为内在膜蛋白或脂锚定膜蛋白）和外周膜蛋白（也称为外在膜蛋白）。 在人体中，大约30%的基因组编码膜蛋白。 膜蛋白在生物的生存中发挥多种重要功能，如信号转导、分子或离子转运、酶催化和细胞间通讯等。 膜蛋白在药物开发中也发挥着重要作用。 据报道，目前超过60%的药物靶点均是膜蛋白。
Chem960可以提供关于膜蛋白靶向小分子抑制剂化合物，可以用于膜蛋白靶向筛选或药物开发。
• A unique collection of 384 small molecules targeting variety of membrane proteins.
• Targets such as GLUT, GABA Receptor, VEGFR, GPR88, Adrenergic Receptor, 5-HT Receptor, ion channel, etc.
• All of the small molecules in this library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.
• A powerful tool for discovering membrane protein-based drugs.
• Structurally diverse, medicinally active, and cell permeable.
• NMR and HPLC validated to ensure the highest purity.
• All compounds are in stock and continuously updated.
