氧化应激是由于体内活性氧与抗氧化剂失衡产生的，可以导致细胞和组织的损伤。氧化应激可诱发多种疾病的发生，包括慢性疾病及退行性疾病，以及加速身体衰老过程和引起急性病理。抗氧化剂是一类能够对抗氧化应激并减轻其对人体损伤的一类化合物，受到了生物医学研究界的极大关注。长期以来，抗氧化剂一直是治疗诸如阿尔兹海默症和癌症等多种疾病的重要药物。
Chem960 抗氧化化合物库包括 对氧化应激具有抑制作用的小分子化合物，可以用于高通量筛选和高内涵筛选。该化合物库是开发新的抗氧化剂，研究氧化应激的有用工具。
• A unique collection of 473 compounds that act as antioxidants for high throughput screening (HTS) and high content screening (HCS).
• Targets such as NF-κB, mTOR, Keap1-Nrf2, AMPK, Sirtuin, etc.
• Bioactivity and safety confirmed by preclinical research and clinical trials, some compounds have been approved by FDA.
• A useful tool to study oxidative stress.
• More detailed compound information with structure, IC50, and other chemical & biological data.
• NMR and HPLC validated ensure high purity.
• All compounds are in stock and continuously updated.
