骨化是一个严格调控的过程，由一种叫做成骨细胞的特殊细胞完成。这一过程的失调可能导致骨骼矿化不足或过度或异位钙化，所有这些都会对人类健康产生严重影响。
成骨细胞在骨形成和预防骨坏死过程中发挥着重要作用。而成骨细胞和骨形成受激素、生长因子、细胞因子等调节。
Chem960精心收录了关于骨生成小分子抑制剂化合物，具有明确和潜在的诱导成骨活性。Chem960骨生成化合物库是研究骨病药物和药理学的有用工具。
• A unique collection of 261 bone formation compounds for high throughput screening (HTS) and high content screening (HCS).
• A useful tool for the study of bone disease drugs and pharmacology.
• Target diverse, medicinally active and cell permeable.
• Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.
• More detailed compound information with structure, IC50, and other chemical & biological data.
• High purity and quality validated by NMR and LC/MS.
