核受体，是在细胞中发现的一类蛋白质，负责感知雄激素、甲状腺激素和某些其他分子。它是一种参与人体生理病理等多方面的配体激活转录因子，调节多种重要基因的表达。
核受体已成为新药开发策略中的主要靶点之一，为研究多种人类疾病提供了一种独特的受体，如乳腺癌、皮肤病和糖尿病等。13%的美国食品和药物管理局(FDA)批准的药物靶向核受体。
Chem960可以提供关于核受体抑制剂化合物，所有化合物均明确报道对核受体有抑制作用。Chem960核受体库是癌症、皮肤病和糖尿病等相关药物研究的有用工具。
• A unique collection of 124 nuclear receptor inhibitors and activators for high throughput screening (HTS) and high content screening (HCS).
• A useful tool for studying the relationship between diseases and nuclear receptor.
• Target diverse, medicinally active and cell permeable.
• Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.
• More detailed compound information with structure, IC50, and other chemical & biological data.
• High purity and quality validated by NMR and LC/MS.
