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抗肿瘤天然产物库 - Anti-Cancer Natural Product Library

天然产物由于其空间结构及生物活性的多样性,一直是先导化合物及新药开发的重要来源。在开发和发现多种治疗人类疾病的新药上发挥着重要作用,特别是抗肿瘤及抗感染药物开发方面表现突出。大量来自植物、动物、海洋生物和微生物的天然产物已被证明具有明确或潜在的抗肿瘤活性。目前,超过60%的抗肿瘤药物都从天然来源中提取,其中在乳腺癌,前列腺癌,结肠癌等领域应用较为广泛。

chem960提供了 1412 种具有明确抗肿瘤活性的天然产物。chem960抗肿瘤天然产物库是抗肿瘤药物筛选等相关研究的有用工具。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 chem960 抗肿瘤天然产物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,1364 个产品以 10 mM 浓度提供,33 个产品以 2 mM 浓度提供,15 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

生物活性

•   A unique collection of 1412 natural products with validated and potential anti-cancer activity for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of anti- cancer drugs.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.


天然产物库详情
Formulation:
A collection of 1412 natural products supplied as pre-dissolved Solutions or Solid
Solution:1364 compounds supplied in 10 mM solution,33 compounds supplied in 2 mM solution,15 compounds supplied in 3 mg/mL solution.
Layout:
96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
-80°C

化合物库组成

上海源叶生物科技有限公司
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