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生物碱化合物库 - Alkaloids Library

生物碱是一大类复杂的含氮的碱性有机化合物,大多数生物碱都有复杂的环状结构,氮多包含在环内。目前已经分离得到 2000 多种生物碱化合物。一些重要的生物碱包括**、士的宁、阿托品、秋水仙碱、麻黄碱、奎宁和尼古丁等。生物碱作为食品,营养品及药物,在医药及其他领域中发挥重要作用。生物碱化合物在抗炎、抗癌、止痛、局部麻醉、神经药理、抗细菌、抗真菌等方面表现出较好的生物活性。此外,生物碱也是有机合成中重要的化合物,可以用于寻找新的半合成和合成化合物,可能具有比母体化合物更好的生物活性。

chem960 收录了 448 个来自天然产物的生物碱化合物。chem960 生物碱化合物库是新药开发的有用工具,可以用于高通量和高内涵筛选。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 chem960 生物碱化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,428 个产品以 10 mM 浓度提供,18 个产品以 2 mM 浓度提供,2 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

生物活性

•   A unique collection of 448 alkaloids for high throughput screening (HTS) and high content screening (HCS).

•   The compounds in the library contain indoles, quinolines, isoquinolines, pyrrolidines, pyridines, pyrrolizidines, tropanes, and terpenoids and steroids.

•   A useful tool for drug discovery as an important source of lead compounds.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.


天然产物库详情
Formulation:
A collection of 448 bioactive Alkaloids supplied as pre-dissolved Solutions or Solid
Solution:428 compounds supplied in 10 mM solution,18 compounds supplied in 2 mM solution,2 compounds supplied in 3 mg/mL solution.
Layout:
96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice

化合物库组成

上海源叶生物科技有限公司
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