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| 公司名 | BOC Sciences |
| 联系人 | Linna Green |
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| 中文名 | 伊利司莫 |
| 英文名 | Elesclomol |
| 别名 | 伊利司莫;伊利司莫 ELESCLOMOL;丙二酸-1,3-二[2-甲基-2-(苯基硫酮甲基)酰肼] |
| CAS | 488832-69-5 |
| EINECS | |
| 化学式 | C19H20N4O2S2 |
| 分子量 | 400.52 |
| inchi | InChI=1/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25) |
| 包装信息 | 25 mg |
| 价格 | $199 |
| 产品描述 | 伊利司莫 Elesclomol is a HSP-90 Inhibitor, and is a small-molecule bis(thio-hydrazide amide) with oxidative stress induction, pro-apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative stress beyond baseline levels elevates ROS beyond sustainable levels, exhausting tumor cell antioxidant capacity, which may result in the induction of the mitochondrial apoptosis pathway. Normal cells are spared because the increase in the level of oxidative stress induced by this agent is below the threshold at which apoptosis is induced. Elesclomol is currently developed by Synta Pharmaceuticals Corp. |
| 产品链接 | http://www.bocsci.com/elesclomol-cas-488832-69-5-item-212109.html |
| 更新日期 | 2025-04-30 11:27:47 |