2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. 1,1'-Bi-2-naphthol

2,2'-Dihydroxy-1,1'-binaphthyl 是一种乙酰胆碱酯酶 (AChE) 抑制剂，对人源 AChE 的 IC50 值为 21.9 μM。2,2'-Dihydroxy-1,1'-binaphthyl 对卤虫无节幼体具有细胞毒性。

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1,1'-Bi-2-naphthol

1,1'-Bi-2-naphthol Chemical Structure

CAS No. : 602-09-5

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1,1'-Bi-2-naphthol 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2,2'-Dihydroxy-1,1'-binaphthyl is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 21.9 μM against human AChE. 2,2'-Dihydroxy-1,1'-binaphthyl exhibits cytotoxicity against Artemia nauplii[1].

IC50 & Target

hAChE

21.9 μM (IC50)

体内研究
(In Vivo)


1,1'-Bi-2-naphthol (Compound 2) (10-80 μg/mL，24 小时) 对卤虫无节幼体表现出显著的细胞毒性，其 LD50 为 17.78 μg/mL[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Artemia salina[1]
Dosage: 10, 20, 40, 60, 80 μg/mL
Administration: single dose; 24 h
Result: Calculated an LD₅₀ value of 17.78 μg/mL.
分子量

286.33

Formula

C20H14O2
CAS 号
性状

固体

中文名称

联萘酚
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料
参考文献

1,1'-Bi-2-naphthol 相关分类

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Keywords:

1,1'-Bi-2-naphthol602-09-5联萘酚Cholinesterase (ChE)AChEbrine shrimp naupliiInhibitorinhibitorinhibit

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