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  3. 4'-Acetoxy resveratrol

4'-Acetoxy resveratrol 是 Resveratrol (HY-16561) 的衍生物。4'-Acetoxy resveratrol 在人体皮肤模型中,可上调弹性蛋白、III 型和 IV 型胶原蛋白 (collagen)、超氧化物歧化酶 (SOD) 和过氧化氢酶 (CAT) 的基因表达,同时下调白细胞介素 (IL-1AIL-1R2IL-6IL-8) 和环氧合酶 -2 (COX-2) 的表达。4'-Acetoxy resveratrol 可用于皮肤研究。

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4'-Acetoxy resveratrol

4'-Acetoxy resveratrol Chemical Structure

CAS No. : 411233-11-9

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  • 生物活性

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生物活性

4'-Acetoxy resveratrol is a Resveratrol (HY-16561) derivative. 4'-Acetoxy resveratrol upregulates gene expression of elastin, collagen types III and IV, superoxide dismutase (SOD), and catalase (CAT), while downregulating interleukins (IL-1A, IL-1R2, IL-6, IL-8) and cyclooxygenase-2 (COX-2) in human skin models. 4'-Acetoxy resveratrol can be used for skin reasearch[1][2].

IC50 & Target[1]

COX-2

 

Collagen III

 

Collagen IV

 

IL-6

 

IL-8

 

IL-1A

 

IL-1R2

 

分子量

270.28

Formula

C16H14O4

CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
4'-Acetoxy resveratrol
目录号:
HY-171657
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