2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. 4-Hydroxytryptophol

4-Hydroxytryptophol 是 psilocin 的体外代谢物，可存在于人肝微粒体和重组单胺氧化酶 A 体系中。4-Hydroxytryptophol 在小鼠或人的体内样本中未被检测到。

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4-Hydroxytryptophol

4-Hydroxytryptophol Chemical Structure

CAS No. : 1379213-90-7

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4-Hydroxytryptophol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4-Hydroxytryptophol is an in vitro metabolite of psilocin, can be found in human liver microsomes and recombinant monoamine oxidase A systems. 4-Hydroxytryptophol is not detected in in vivo samples from mice or humans[1].

体外研究
(In Vitro)

4-Hydroxytryptophol 在 1,000 nM psilocin 与人肝微粒体共同孵育 240 分钟时，以少量 (43.4 nM) 生成，同时裸盖菇素浓度下降 29%[1]。
4-Hydroxytryptophol 在 1000 nM psilocin 与重组 MAO-A 酶共孵育 300 分钟时仅以微量 (16.9 nM) 生成，且 psilocin 浓度未出现可见下降[1]。
4-Hydroxytryptophol 对 HEK 293 细胞系膜制品中的人源 5-HT1A、5-HT2A和 5-HT2C受体无显著结合亲和力 (Ki > 10,000 nM)[1]。
4-Hydroxytryptophol 在 NIH/3T3 细胞中对人源 5-HT1A、5-HT2A和 5-HT2B受体无显著激活活性 (EC50 > 10,000 nM)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

4-Hydroxytryptophol 相关抗体:
分子量

177.20

Formula

C10H11NO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

4-Hydroxytryptophol 相关分类

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  • 稀释计算器

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Keywords:

4-Hydroxytryptophol1379213-90-74-HTPDrug Metabolitehuman liver microsomesmicehuman 5-HT?A receptorsrecombinant monoamine oxidase A systemsNIH/3T3 cellshuman 5-HT?B receptorsHEK 293 cell linepsilocinhuman 5-HT?C receptorsInhibitorinhibitorinhibit

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