2. Others
  3. Drug Derivative
  4. 5α-Cyprinol sulfate

5α-Cyprinol sulfate 是一种具有口服活性的胆汁盐和异种化感信息素。5α-Cyprinol sulfate 可促进鱼类的脂质消化。5α-Cyprinol sulfate 可抑制大鼠回肠顶端胆汁盐转运体介导的牛磺胆酸摄取。5α-Cyprinol sulfate 可用于鱼类毒性急性肾衰竭的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

5α-Cyprinol sulfate

5α-Cyprinol sulfate Chemical Structure

CAS No. : 53939-19-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

5α-Cyprinol sulfate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5α-Cyprinol sulfate is an orally active bile salt and heterospecific pheromone. 5α-Cyprinol sulfate promotes lipid digestion in fish. 5α-Cyprinol sulfate inhibits taurocholic acid uptake mediated by apical bile salt transporters in rat ileum. 5α-Cyprinol sulfate can be used in studies of fish toxic acute renal failure[1][2].

体外研究
(In Vitro)

5α-Cyprinol sulfate (100-10700 pM; day 3 or 4 of incubation) 可在浓度≥100 pM 时诱导大型溞产生昼夜垂直迁移 (增加白天栖息深度)，其活性阈值浓度为 100 pM[1]。
5α-Cyprinol sulfate (100 μM; 15 min at 37°C) 可完全抑制瞬时转染回肠顶端胆盐转运体 (asbt) 的 COS-7 细胞中钠依赖性牛磺胆酸摄取[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

5α-Cyprinol sulfate 相关抗体:
体内研究
(In Vivo)

5α-Cyprinol sulfate (1 μmol/min/kg; i.v.; single infusion) 经静脉给予麻醉大鼠后，会诱导溶血、胆道出血和死亡[2]。
5α-Cyprinol sulfate (1-4 μmol/min/kg; i.v. into perfused liver; 20-minute infusion) 在离体灌流大鼠肝脏中给药后，表现出 0.5 μmol/kg/min 的最大胆汁分泌速率 (Tmax)，在高剂量下会减少胆汁流量，并且竞争性抑制牛磺胆酸的肝脏摄取与分泌[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: unspecified strain (isolated perfused liver model)[2]
Dosage: 1 μmol/min/kg; 4 μmol/min/kg
Administration: i.v. into perfused liver; 20-minute infusion
Result: Achieved hepatic uptake exceeding 90% during infusion and recovery of 65.3 (n=6) at 1 μmol/min/kg.
Reached biliary secretion peak of unchanged reagent and minor disulfate metabolite at 30 minutes, with maximal secretion rate of 0.5 μmol/kg/min at 1 μmol/min/kg.
Showed no significant increase in bile flow at 1 μmol/min/kg.
Resulted in extremely low recovery of 17.0% at 4 μmol/min/kg.
Reduced bile flow immediately upon infusion, with gradual recovery over the experiment at 4 μmol/min/kg.
Caused dose-dependent reduction in taurocholate uptake and biliary recovery in competition experiments; effect reversed immediately when infusion stopped.
分子量

532.73

Formula

C27H48O8S
CAS 号
结构分类
初始来源

carp
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5α-Cyprinol sulfate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5α-Cyprinol53939-19-8Drug DerivativeDrug derivativemonooleylglycerolDaphnia magnataurocholatekairomonerat apical ileal bile salt transportercarpfishcyprinid fishmicellesbile saltInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
5α-Cyprinol sulfate
目录号：
HY-N18490
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z