2. Anti-infection Metabolic Enzyme/Protease
  3. Parasite HIV HIV Protease
  4. 5-Hydroxynoracronycine

5-Hydroxynoracronycine 是靶向利什曼原虫、HIV-1 蛋白酶及一氧化氮 (NO) 生成的选择性抑制剂。5-Hydroxynoracronycine 抗 HIV-1 蛋白酶的 IC50 为 93.1 μmol/L，清除 DPPH 自由基的 IC50 为 0.19 mg/mL。5-Hydroxynoracronycine 通过抑制病原体增殖、酶活性及炎症相关 NO 过度产生发挥抗利什曼原虫、抗 HIV、抗氧化及抗菌活性。5-Hydroxynoracronycine 可用于利什曼病、HIV 感染、炎症相关疾病的研究。

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5-Hydroxynoracronycine

5-Hydroxynoracronycine Chemical Structure

CAS No. : 27067-70-5

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5-Hydroxynoracronycine 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

查看所有亚型
Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

查看 HIV 亚型特异性产品:

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HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5-Hydroxynoracronycine is a selective inhibitor targeting Leishmania, HIV-1 protease, and nitric oxide (NO) production. 5-Hydroxynoracronycine has an IC50 of 93.1 μmol/L against HIV-1 protease and an IC50 of 0.19 mg/mL for scavenging DPPH free radicals. 5-Hydroxynoracronycine exerts anti-leishmanial, anti-HIV, antioxidant and antibacterial activities by inhibiting pathogen proliferation, enzyme activity and inflammation-related NO excessive production. 5-Hydroxynoracronycine can be used in the research of leishmaniasis, HIV infection, and inflammation-related diseases[1][2].

IC50 & Target

HIV-1

 

体外研究
(In Vitro)

5-Hydroxynoracronycine 对婴儿利什曼原虫前鞭毛体 (promastigotes) 48 小时的 EC50 为 4.42 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

5-Hydroxynoracronycine 相关抗体:
分子量

323.34

Formula

C19H17NO4
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5-Hydroxynoracronycine 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

5-Hydroxynoracronycine27067-70-5ParasiteHIVHIV ProteaseHuman immunodeficiency virusInhibitorinhibitorinhibit

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