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  3. 6-Isopentenyloxyisobergapten

6-Isopentenyloxyisobergapten 是一种存在于大瓣芹 (Semenovia transiliensis) 地上部分和 Heracleum maximum 根中的呋喃香豆素。6-Isopentenyloxyisobergapten 兼具选择性植物毒性与抗结核活性。6-Isopentenyloxyisobergapten 对结核分枝杆菌 H37Ra 的最低抑菌浓度 (MIC) 为 166.5 μM、半数抑制浓度 (IC50) 为 27.4 μM。6-Isopentenyloxyisobergapten 对浮萍 (Lemna paucicostata) 生长抑制作用的 IC50 为 29 μM, 在 1000 μM 浓度下对匍匐剪股颖 (Agrostis stolonifera) 的活性高于莴苣 (Lactuca sativa)。

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6-Isopentenyloxyisobergapten

6-Isopentenyloxyisobergapten Chemical Structure

CAS No. : 24099-29-4

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  • 生物活性

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生物活性

6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC50 of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC50 of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM[1][2].

体外研究
(In Vitro)

6-Isopentenyloxyisobergapten (compound 4) (10-1000 μM; 7 days) 对 Agrostis stolonifera 种子的植物毒性抑制活性强于 Lactuca sativa 种子的活性[1]
6-Isopentenyloxyisobergapten (10-1000 μM; 4 days) 对 Lemna paucicostata 植株具有浓度依赖性的生长抑制活性,其对该植株生长抑制的 IC50 为 29 μM[1]
6-Isopentenyloxyisobergapten (compound 8) 对结核分枝杆菌 H37Ra 表现出显著的抗分枝杆菌活性,其最小抑菌浓度 (MIC) 为 166.5 μM,IC50 为 27.4 μM[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

300.31

Formula

C17H16O5

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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6-Isopentenyloxyisobergapten
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