2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. 8-Hydroxydihydrochelerythrine

8-Hydroxydihydrochelerythrine  (Synonyms: 8-羟基二氢白屈菜红碱)

目录号: HY-N18289
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8-Hydroxydihydrochelerythrine 是一种苯并菲啶类生物碱衍生的、选择性和竞争性 AChE 抑制剂 (IC50=0.61 μM)，可从两面针 (Roxb.) DC 的根中分离得到。8-Hydroxydihydrochelerythrine 可提高胆碱能神经元突触间乙酰胆碱的含量，增强胆碱能神经传递。8-Hydroxydihydrochelerythrine 可用于阿尔茨海默病等痴呆类神经系统疾病的研究。

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8-Hydroxydihydrochelerythrine

8-Hydroxydihydrochelerythrine Chemical Structure

CAS No. : 4070-42-2

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8-Hydroxydihydrochelerythrine 相关抗体

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AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

8-Hydroxydihydrochelerythrine is a benzophenanthridine alkaloid-derived, selective and competitive AChE inhibitor (IC50=0.61 μM) isolated from the roots of Zanthoxylum nitidum (Roxb.) DC. 8-Hydroxydihydrochelerythrine increases the content of acetylcholine in the synapses of cholinergic neurons and enhances cholinergic neurotransmission. 8-Hydroxydihydrochelerythrine is applicable to the research of neurodegenerative diseases with dementia such as Alzheimer's disease[1][2].

IC50 & Target

AChE

0.61 μM (IC50)

BChE

34.6 μM (IC50)

AChE

0.25 μM (Ki)

分子量

365.38

Formula

C21H19NO5
CAS 号
中文名称

8-羟基二氢白屈菜红碱
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

8-Hydroxydihydrochelerythrine 相关分类

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Keywords:

8-Hydroxydihydrochelerythrine4070-42-28-羟基二氢白屈菜红碱Cholinesterase (ChE)rootsbenzophenanthridine alkaloid derivativeZanthoxylum nitidum (Roxb.) DCdried root tissueInhibitorinhibitorinhibit

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