Plasminogen/Plasmin (纤溶酶原/纤溶酶)

Plasmin, the proteolytically active form of plasminogen, utilizes fibrin contained within clots as a substrate for proteolysis, producing soluble products and thus maintaining the patency within the vascular system. The precursor to plasmin, plasminogen, serves as zymogen produced by the liver circulates throughout the endovascular network, and participates in the fibrinolytic pathway, serving as both a catalytic enzyme to initiate the process of fibrinolysis, as well as a substrate, which once cleaved to become plasmin, continues on the process of fibrinolysis at an accelerated rate.