2. Others PI3K/Akt/mTOR Stem Cell/Wnt
  3. Reference Standards GSK-3
  4. A 1070722 (Standard)

A 1070722 (Standard) 是 A 1070722 (HY-107531) 的分析标准品。本产品用于研究及分析应用。A 1070722 是一个高效、选择性的糖原合成酶激酶 3 (GSK-3) 抑制剂，对 GSK-3α 和 GSK-3β 作用的 Ki 为 0.6 nM。A 1070722 能穿透血脑屏障并在脑区积聚，具有作为定量测定脑部 GSK-3 的 PET 放射性跟踪剂的潜力。A 1070722 抑制自发运动。

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A 1070722 (Standard)

A 1070722 (Standard) Chemical Structure

CAS No. : 1384424-80-9

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A 1070722 (Standard) 相关抗体

Top Publications Citing Use of Products

查看 GSK-3 亚型特异性产品:

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GSK-3 GSK-3α GSK-3β

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A 1070722 (Standard) is the analytical standard of A 1070722 (HY-107531). This product is intended for research and analytical applications. A 1070722 is a potent and selective glycogen synthase Kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain. A 1070722 decreases spontaneous locomotion[1][2].

IC50 & Target

Ki: 0.6 nM (GSK-3)[1]
分子量

362.31

Formula

C17H13F3N4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

A 1070722 (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A 1070722 (Standard)1384424-80-9Reference StandardsGSK-3Glycogen synthase kinase-3Glycogen synthase kinase 3ratsspontaneous locomotionPETInhibitorinhibitorinhibit

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