2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. AChE-IN-106

AChE-IN-106 是一种 AChE 抑制剂。AChE-IN-106 在低浓度下无明显细胞毒性。AChE-IN-106 可用于阿尔茨海默病的研究。

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AChE-IN-106

AChE-IN-106 Chemical Structure

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AChE-IN-106 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AChE-IN-106 is an AChE inhibitor. AChE-IN-106 shows no obvious cytotoxicity at low concentrations. AChE-IN-106 can be used for the research of Alzheimer's disease[1].

IC50 & Target[1]

AChE

 

体外研究
(In Vitro)

AChE-IN-106 (Compound 6j) (0-500 μM；24 h) 在 SH-SY5Y 细胞中安全性较好[1]。
AChE-IN-106 (15.62 μM；24 h) 可强效抑制 Aβ 诱导的 SH-SY5Y 细胞中的 AChE 活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AChE-IN-106 相关抗体:

Cell Viability Assay[1]

Cell Line: SH-SY5Y human neuroblastoma cells
Concentration: 0, 15.62, 31.25, 62.5, 125, 250 and 500 μM
Incubation Time: 24 h
Result: Maintained 96.138% cell viability relative to untreated controls at 15.62 μM.
Decreased viability in a dose-dependent manner to 89.631% at 31.25 μM, 84.379% at 62.5 μM, 79.899% at 125 μM, 65.012% at 250 μM, and 42.035% at 500 μM.
分子量

314.19

Formula

C13H9Cl2NO2S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AChE-IN-106 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE-IN-106Cholinesterase (ChE)AβSH-SY5Y cellsalzheimer's diseaseADInhibitorinhibitorinhibit

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产品名称：
AChE-IN-106
目录号：
HY-181119
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