2. Others MAPK/ERK Pathway Apoptosis
  3. Reference Standards JNK Apoptosis
  4. AEG3482 (Standard)

AEG3482 (Standard) 是 AEG3482 (HY-107599) 的分析标准品。本产品用于研究及分析应用。AEG3482 是一种有效的抗凋亡化合物，可诱导热休克蛋白 70 (HSP70) 的表达来抑制 JNK 活性。AEG3482 通过直接结合 HSP90，从而促进 HSP70 和 HSP25 的 HSF1 依赖性表达。

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AEG3482 (Standard)

AEG3482 (Standard) Chemical Structure

CAS No. : 63735-71-7

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AEG3482 (Standard) 相关抗体

Top Publications Citing Use of Products

查看 JNK 亚型特异性产品:

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JNK1 JNK2 JNK3 JNK

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AEG3482 (Standard) is the analytical standard of AEG3482 (HY-107599). This product is intended for research and analytical applications. AEG3482 is a potent antiapoptotic compound that inhibits Jun Kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25[1].

IC50 & Target

JNK[1]
分子量

280.33

Formula

C10H8N4O2S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AEG3482 (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AEG3482 (Standard)63735-71-7Reference StandardsJNKApoptosisc-Jun N-terminal kinaseantiapoptoticJunkinaseheatshockprotein70HSP70HSP90HSF1Inhibitorinhibitorinhibit

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