2. Metabolic Enzyme/Protease
  3. Glycosidase
  4. α-Glucosidase-IN-112

α-Glucosidase-IN-112 是一种 α-葡萄糖苷酶 (α-glucosidase) 抑制剂，其 IC50 为 2.03 μM，Ki 为 0.44 μM。α-Glucosidase-IN-112 可通过清除 ABTS+ 自由基发挥抗氧化作用。α-Glucosidase-IN-112 可通过抑制膀胱癌细胞增殖发挥抗增殖效应。α-Glucosidase-IN-112 可用于 2 型糖尿病和膀胱癌的相关研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

α-Glucosidase-IN-112

α-Glucosidase-IN-112 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

α-Glucosidase-IN-112 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

α-Glucosidase-IN-112 is an α-glucosidase inhibitor with an IC50 of 2.03 μM and a Ki of 0.44 μM. α-Glucosidase-IN-112 exerts antioxidant effects by scavenging ABTS+ free radicals. α-Glucosidase-IN-112 exerts antiproliferative effects by inhibiting the proliferation of bladder cancer cells. α-Glucosidase-IN-112 can be used in research related to type 2 diabetes and bladder cancer[1].

IC50 & Target[1]

α‑glucosidase

2.03 μM (IC50)

α‑glucosidase

0.44 μM (Ki)

体外研究
(In Vitro)

α-Glucosidase-IN-112 (Compound 4i) (0-2.0 μM; 24 h) 可强效抑制人 T24 膀胱癌细胞的增殖，其 IC50 为 1.93 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

α-Glucosidase-IN-112 相关抗体:

Cell Proliferation Assay[1]

Cell Line: human T24 bladder cancer cells
Concentration: 0, 0.5, 1, 1.5 and 2.0 μM
Incubation Time: 24 h
Result: Inhibited T24 bladder cancer cell proliferation with an IC50 value of 1.93 μM, which is lower than the IC50 value of the positive control cisplatin.
分子量

466.58

Formula

C23H22N4O3S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

α-Glucosidase-IN-112 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Glucosidase-IN-112Glycosidasetype-2 diabetesSaccharomyces cerevisiaebladder cancer cellsα-glucosidaseMM/PBSA binding free energybladder cancerhuman T24 bladder cancer cellsamino acid residuesABTS+ free radicalsactive siteInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
α-Glucosidase-IN-112
目录号：
HY-181353
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z