2. GPCR/G Protein
  3. Bombesin Receptor
  4. AMBA

AMBA 是一种胃泌素释放肽受体 (GRPR、BB2、BRS-2) 配体，对人源的 IC50 为 0.82 nM，人源 Ki 为 0.65 nM。AMBA 可高特异性、高亲和力结合 GRPR，并发生受体介导的内吞作用，使偶联的放射性金属滞留在靶细胞内。AMBA 可用于前列腺癌的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

AMBA

AMBA Chemical Structure

CAS No. : 721937-56-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

AMBA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AMBA is a gastrin-releasing peptide receptor (GRPR, BB2, BRS-2) ligand with a human IC50 of 0.82 nM and a human Ki of 0.65 nM. AMBA binds to GRPR with high specificity and high affinity, and undergoes receptor-mediated endocytosis, which retains the conjugated radiometal in target cells. AMBA is applicable for the research of prostate cancer[1].

体外研究
(In Vitro)

AMBA (0.001-1000 nmol/L; 60 min) 对人 GRPR 受体具有高特异性和纳摩尔级亲和力，其 IC50 为 0.82 nmol/L，Ki 为 0.65 nmol/L[1]。
AMBA (6.66 × 10-4 μmol (1 μg); 10 min) 可被 111In 高效放射性标记，在测试条件下的标记效率达 95.43%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AMBA 相关抗体:
体内研究
(In Vivo)

111In-AMBA (0.37 MBq-12.2 MBq/4 μg; 静脉注射；单次给药) 在接种 PC-3 前列腺肿瘤的 SCID 小鼠中，于注射后 8 h 达到 3.87% ID/g 的肿瘤摄取峰值，肿瘤/肌肉比最高可达 11.79，表明其可有效靶向表达 GRPR 的肿瘤[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1502.70

Formula

C68H99N19O18S
CAS 号
Sequence

{DOTA}-Gly-{PAB}-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
Sequence Shortening

{DOTA}-G-{PAB}-QWAVGHLM-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AMBA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AMBA721937-56-0Bombesin ReceptorSCID micehuman bombesin 2 receptorsmicroSPECT/CT imagingPC-3 prostate tumorprostate tumorsGRPRprostate cancergastrin-releasing peptide receptorInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
AMBA
目录号：
HY-P11768
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z