2. Anti-infection
  3. EBV
  4. Amygdalinic acid

Amygdalinic acid (Compound 3) 是一种糖苷。Amygdalinic acid 可从桃仁 (Persicae Semen) 中分离得到。Amygdalinic acid 可抑制 EB 病毒早期抗原 (Epstein-Barr virus early antigen) 的激活。Amygdalinic acid 可延缓小鼠皮肤的两阶段化学致癌过程，降低乳头状瘤的发生率。

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Amygdalinic acid

Amygdalinic acid Chemical Structure

CAS No. : 66427-92-7

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Amygdalinic acid 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Amygdalinic acid (Compound 3) is a glycoside. Amygdalinic acid can be isolated from Persicae Semen. Amygdalinic acid inhibits Epstein-Barr virus early antigen activation. Amygdalinic acid delays two-stage chemical carcinogenesis in mouse skin, reduces papilloma incidence[1].

体外研究
(In Vitro)

Amygdalinic acid (10-1000 mol ratio/TPA; 48 h) 可浓度依赖性地抑制 Raji 细胞中 EBV-EA 的激活，在 1000 mol ratio/TPA 时抑制作用最强 (相对对照组为 3.5%)，同时细胞存活率为 60%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Amygdalinic acid 相关抗体:

Immunofluorescence[1]

Cell Line: Raji cells (Burkitt's lymphoma-derived lymphoblastoid cells)
Concentration: 10-1000 mol ratio/TPA
Incubation Time: 48 h
Result: Reduced EBV-EA activation to 3.5 ± 0.3% relative to the positive control, with 60% Raji cell viability at 1000 mol ratio/TPA.
Reduced EBV-EA activation to 34.1 ± 1.2% relative to the positive control, with >80% Raji cell viability at 500 mol ratio/TPA.
Reduced EBV-EA activation to 65.0 ± 1.9% relative to the positive control, with >80% Raji cell viability at 100 mol ratio/TPA.
Reduced EBV-EA activation to 95.7 ± 0.4% relative to the positive control, with >80% Raji cell viability at 10 mol ratio/TPA.
体内研究
(In Vivo)

Amygdalinic acid (85 nmol； 每周两次) 在小鼠两阶段皮肤致癌模型中表现出抗肿瘤促发活性，将乳头状瘤的发生水平降至与 (-)-Epigallocatechin gallate (HY-13653) 相当的程度[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

476.43

Formula

C20H28O13
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Amygdalinic acid 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amygdalinic acid66427-92-7EBVEpstein-Barr VirusAC755 tumor cells12-O-tetradecanoylphorbol 13-acetatePrunus persicaEpstein-Barr virus early antigenskin papilloma(-)-epigallocatechin gallateRaji cellsmouse two-stage skin carcinogenesis modelmouse skinInhibitorinhibitorinhibit

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