2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 336

Antibacterial agent 336 是一种抗菌 (antibacterical) 剂，对革兰氏阴性菌和革兰氏阳性菌具有广谱抑制活性。Antibacterial agent 336 通过其吡啶基团与 MsbA 蛋白的羧基、Lys-465 残基及 Leu-480 残基紧密结合，干扰细菌外膜合成，并对细菌发挥浓度依赖性杀菌活性。Antibacterial agent 336 对人正常肝细胞的细胞毒性较低。Antibacterial agent 336 可用于细菌感染的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Antibacterial agent 336

Antibacterial agent 336 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Antibacterial agent 336 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 336 is an antibacterical agent with broad-spectrum inhibitory activity against Gram-negative and Gram-positive bacteria. Antibacterial agent 336 binds tightly via its pyridine group to the carboxyl group, Lys-465 residue, and Leu-480 residue of the MsbA protein, interfering with bacterial outer membrane synthesis, and exerts concentration-dependent bactericidal activity against bacterial. Antibacterial agent 336 has low cytotoxicity to normal human liver cells. Antibacterial agent 336 can be used for the research of bacterial infections[1].

体外研究
(In Vitro)

Antibacterial agent 336 (Compound z10) 具有广谱的体外抗菌活性，对 E. coli ATCC 25922、Salmonella ATCC 12022、S. aureus ATCC 25922 和 P. aeruginosa ATCC 27853 的 MIC 值分别为 1.40、1.40、1.75 和 2.33 μM[1]。
Antibacterial agent 336 对人正常肝细胞 L02 表现出较低的体外细胞毒性，其 IC50 为 378.6 μM，选择性指数为 216.3[1]。
Antibacterial agent 336 (0.5×MIC-2×MIC; 2-25 h) 对 E. coli ATCC 25922、P. aeruginosa ATCC 27853、Salmonella ATCC 12022 及 S. aureus ATCC 25922 具有浓度依赖性杀菌作用，在 1×MIC 和 2×MIC 浓度下，2 小时内即可观察到显著的细菌杀灭效果[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 336 相关抗体:
分子量

428.55

Formula

C22H28N4O3S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 336 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 336Antibacterial agent336Antibacterial agent-336BacterialMsbA proteinP. aeruginosa ATCC 27853S. aureus ATCC 25922Gram-negative bacteriabacterial outer membrane synthesisSalmonella ATCC 12022normal human liver L02 cellsnormal human liver cellsGram-positive bacteriaE. coli ATCC 25922Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Antibacterial agent 336
目录号：
HY-182784
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z