PDCD4 抗体 (YA240)

目录号: HY-P80269 一键复制产品信息: Data Sheet SDS COA 抗体使用指南
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PDCD4 Antibody (YA240) 是一个兔来源、无偶联标记、抗 PDCD4 的 IgG 单克隆抗体。

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规格	价格	是否有货
10 μL	￥493	In-stock
50 μL	￥1281	In-stock
100 μL	￥2100	In-stock
250 μL		询价

or 大包装询价

* Please select Quantity before adding items.

WB: 蛋白质免疫印迹;
IHC-P: 石蜡切片样本的免疫组织化学;
IHC-F: 冰冻切片样本的免疫组织化学;
ICC/IF: 细胞免疫荧光;
IF-Tissue: 组织免疫荧光;
mIHC: 多重荧光免疫组化;
IP: 免疫沉淀;
ChIP: 染色质免疫沉淀;
FC: 流式细胞术;
ELISA: 酶联免疫吸附试验

产品详情
验证图片
背景信息
产品资料

描述

PDCD4 Antibody (YA240) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PDCD4.

宿主

Rabbit

克隆性

Recombinant,Monoclonal

分子量

Predicted band size: 52 kDa;

Observed band size: 56 kDa

请注意：因蛋白存在修饰或聚体等情况，以实测为准，预测仅为参考。

反应种属

Human, Mouse

蛋白数据库

Q53EL6

基因 ID

27250 [NCBI]

免疫原

Synthetic peptide corresponding to Human PDCD4.AA range:425-469.

应用 & 推荐
稀释比例

应用	稀释比
WB WB: 蛋白质免疫印迹	1:500
ICC/IF ICC/IF: 细胞免疫荧光	1:20-1:50
IHC-P IHC-P: 石蜡切片样本的免疫组织化学	1:50-1:200
FC FC: 流式细胞术	1:50-1:100

敏感性	Endogenous	纯度	Protein A affinity purified.
偶联	Non-conjugated	修饰	Unmodified
同型	IgG

性状

液体

组分

Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.

保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

运输条件

Shipping with blue ice.

验证图片

IHC

Immunohistochemical analysis of paraffin-embedded human Breast Cancer tissue using PDCD4 antibody was performed. The section was pretreated using high-temperature and high-pressure mediated EDTA antigen retrieval buffer (pH 9.0), for 5 minutes. The tissues were incubated with primary antibody (HY-P80269, 1:100 dilution) at room temperature for 60 minutes. Detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. The tissues were counterstained with hematoxylin and mounted with neutral balsam mounting medium.
Immunohistochemical analysis of paraffin-embedded human Colon cancer‌ tissue using PDCD4 antibody was performed. The section was pretreated using high-temperature and high-pressure mediated EDTA antigen retrieval buffer (pH 9.0), for 5 minutes. The tissues were incubated with primary antibody (HY-P80269, 1:100 dilution) at room temperature for 60 minutes. Detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. The tissues were counterstained with hematoxylin and mounted with neutral balsam mounting medium.
Immunohistochemical analysis of paraffin-embedded human Ovarian Cancer‌ tissue using PDCD4 antibody was performed. The section was pretreated using high-temperature and high-pressure mediated EDTA antigen retrieval buffer (pH 9.0), for 5 minutes. The tissues were incubated with primary antibody (HY-P80269, 1:100 dilution) at room temperature for 60 minutes. Detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. The tissues were counterstained with hematoxylin and mounted with neutral balsam mounting medium.
Immunohistochemical analysis of paraffin-embedded human Testis tissue using PDCD4 antibody was performed. The section was pretreated using high-temperature and high-pressure mediated EDTA antigen retrieval buffer (pH 9.0), for 5 minutes. The tissues were incubated with primary antibody (HY-P80269, 1:100 dilution) at room temperature for 60 minutes. Detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. The tissues were counterstained with hematoxylin and mounted with neutral balsam mounting medium.
Immunohistochemical analysis of paraffin-embedded human Gastric Cancer tissue using PDCD4 antibody was performed. The section was pretreated using high-temperature and high-pressure mediated EDTA antigen retrieval buffer (pH 9.0), for 5 minutes. The tissues were incubated with primary antibody (HY-P80269, 1:100 dilution) at room temperature for 60 minutes. Detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. The tissues were counterstained with hematoxylin and mounted with neutral balsam mounting medium.
Immunohistochemical analysis of paraffin-embedded human Cervical Cancer‌ tissue using PDCD4 antibody was performed. The section was pretreated using high-temperature and high-pressure mediated EDTA antigen retrieval buffer (pH 9.0), for 5 minutes. The tissues were incubated with primary antibody (HY-P80269, 1:100 dilution) at room temperature for 60 minutes. Detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. The tissues were counterstained with hematoxylin and mounted with neutral balsam mounting medium.

背景

功能：抑制翻译起始和帽依赖性翻译。可能通过阻碍 EIF4A1 和 EIF4G 之间的相互作用发挥功能。抑制 EIF4A 的解旋酶活性。调节 JUN 激酶的激活。下调 MAP4K1 的表达，从而抑制驱动侵袭的重要事件，即 MAPK85 的激活和随后的 JUN 依赖性转录。可能在细胞凋亡中发挥作用。肿瘤抑制因子。抑制肿瘤促进剂诱导的肿瘤转化。通过 RNA 相似性结合。

亚细胞定位：细胞核；细胞质

表达水平：
组织特异性：在增殖细胞中表达上调。在乳腺上皮细胞中高表达。在肺癌和结肠癌中表达降低。

亚基：IL2/白细胞介素-2 刺激抑制表达，而 IL12/白细胞介素-12 刺激则增加表达

RRID

AB_3102391

反应种属数据库

Entrez Gene: 27250 Human ; 18569 Mouse ;

SwissProt: Q53EL6 Human ; Q61823 Mouse ;

OMIM: 608610 Human

研究领域

Cell Biology

中文名

PDCD4 抗体

文件资料

Select Batch:

Data Sheet (443 KB) SDS (251 KB)

COA (194 KB)

抗体使用指南 (1083 KB)

PDCD4 Antibody (YA240) 相关分类

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

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粤ICP备2021105330号-3

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

PDCD4 抗体 (YA240)

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