1. 抗体
  2. 一抗
  3. 单克隆抗体 重组抗体
  4. Stathmin 1 抗体 (YA049)

Stathmin 1 Antibody (YA049) 是一个兔来源、无偶联标记、抗 Stathmin 1 的 IgG 单克隆抗体。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
10 μL ¥493 In-stock
50 μL ¥1281 In-stock
100 μL ¥2100 In-stock
250 μL   询价  

* Please select Quantity before adding items.

  • WB: 蛋白质免疫印迹;
  • IHC-P: 石蜡切片样本的免疫组织化学;
  • IHC-F: 冰冻切片样本的免疫组织化学;
  • ICC/IF: 细胞免疫荧光;
  • IF-Tissue: 组织免疫荧光;
  • mIHC: 多重荧光免疫组化;
  • IP: 免疫沉淀;
  • ChIP: 染色质免疫沉淀;
  • FC: 流式细胞术;
  • ELISA: 酶联免疫吸附试验
  • 产品详情

  • 验证图片

  • 背景信息

  • 产品资料

描述

Stathmin 1 Antibody (YA049) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Stathmin 1.

宿主

Rabbit

克隆性

Recombinant,Monoclonal

分子量
Predicted band size: 17 kDa;
Observed band size: 17 kDa
请注意:因蛋白存在修饰或聚体等情况,以实测为准,预测仅为参考。
反应种属
Human
蛋白数据库
基因 ID
免疫原

Synthetic peptide within Human Stathmin 1 aa 100 to the C-terminus (internal sequence).

应用 & 推荐
稀释比例
应用 稀释比
IHC-P
IHC-P: 石蜡切片样本的免疫组织化学
1:2000
敏感性 Endogenous 纯度 Protein A affinity purified.
偶联 Non-conjugated 修饰 Unmodified
同型 IgG  
性状

液体

组分

Supplied in 1*PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide

保存条件 & 期限

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

运输条件

Shipping with blue ice.

验证图片
IHC-P
  • Immunohistochemical analysis of paraffin-embedded human cervix tissue using Stathmin 1 Antibody (HY-P80348, 1/2000). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • Immunohistochemical analysis of paraffin-embedded human endometrium tissue using Stathmin 1 Antibody (HY-P80348, 1/2000). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • Immunohistochemical analysis of paraffin-embedded human ovary tissue using Stathmin 1 Antibody (HY-P80348, 1/2000). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using Stathmin 1 Antibody (HY-P80348, 1/2000). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using Stathmin 1 Antibody (HY-P80348, 1/2000). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • Immunohistochemical analysis of paraffin-embedded human glioma tissue using Stathmin 1 Antibody (HY-P80348, 1/2000). The section was pretreated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked with quick block buffer for 0.5 hours at room temperature, washed with PBS and PBST, and then incubated with the primary antibody overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

背景
功能:通过破坏微管稳定性参与微管丝系统的调控。抑制微管组装并促进其解聚。Ser-16 位点的磷酸化可能是神经发生过程中轴突形成所必需的。参与控制习得性和先天性恐惧 (基于相似性)。
亚细胞定位:细胞质、细胞骨架
表达水平:
组织特异性:分布广泛。在脑、脊髓和小脑中表达最强,其次是胸腺、骨髓、睾丸和胎肝。在结肠、卵巢、胎盘、子宫和气管中表达中等,在所有其他检测的组织中均能检测到,但水平显著降低。肝脏中的表达最低。

诱导:肠道病毒71型 (EV71) 感染后表达下调 (蛋白质水平)
异构体 & 翻译后修饰:P16949 有两种异构体:P16949-1:17303 Da (预测值);P16949-2:19824 Da (预测值)。
根据可磷酸化位点的特定组合,可观察到许多不同的磷酸化形式。MAPK 负责响应 NGF 而对 stathmin 进行磷酸化。Ser-16 位点的磷酸化似乎是神经元极化所必需的 (基于相似性)。Ser-63 位点的磷酸化可使微管蛋白结合减少 10 倍,并抑制微管聚合抑制活性。
亚基:能与两个α/β-微管蛋白异二聚体结合。与 KIST 相互作用。
RRID
反应种属数据库
研究领域

Neuroscience

中文名
Stathmin 1 抗体 (YA049)
文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Stathmin 1 Antibody (YA049)
目录号:
HY-P80348
需求量: