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  4. Antimalarial agent 56

Antimalarial agent 56 是一种具有口服活性的抗疟疾剂。Antimalarial agent 56 可在体外抑制药物敏感型和耐药型恶性疟原虫 (Plasmodium falciparum) 菌株的生长。Antimalarial agent 56 可用于疟疾的研究。

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Antimalarial agent 56

Antimalarial agent 56 Chemical Structure

CAS No. : 1220533-66-3

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Antimalarial agent 56 相关抗体

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  • 生物活性

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生物活性

Antimalarial agent 56 is an orally active antimalarial agent. Antimalarial agent 56 inhibits the growth of both drug-sensitive and drug-resistant Plasmodium falciparum strains in vitro. Antimalarial agent 56 can be used in malaria research[1].

体外研究
(In Vitro)

Antimalarial agent 56 (WR319535) 可抑制恶性疟原虫 (Plasmodium falciparum) W2、D6、C235 和 C2A 株的生长，其 IC90 值为 75 至 275 ng/mL，且对巨噬细胞的细胞毒性 LC50 为 4110 ng/mL[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antimalarial agent 56 相关抗体:
体内研究
(In Vivo)

Antimalarial agent 56 (WR319535) (160 mg/kg；口服；每日；连续 3 天) 可使感染 Plasmodium berghei 的 ICR 小鼠的死亡时间延迟 7 天[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR mice[1]
Dosage: 160 mg/kg
Administration: p.o.; daily; 3 consecutive days
Result: Produced a 7-day delay in mortality relative to vehicle control.
分子量

433.39

Formula

C20H21F6N3O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antimalarial agent 56 相关分类

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Keywords:

Antimalarial agent 561220533-66-3Antimalarial agent56Antimalarial agent-56ParasitePlasmodium falciparumD6 strainC235 strainmacrophageMDR1-transfected MDCK cell monolayersmalariaICR mousePlasmodium bergheiC2A strainW2 strainInhibitorinhibitorinhibit

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