2. Anti-infection Cell Cycle/DNA Damage
  3. Orthopoxvirus DNA/RNA Synthesis
  4. Antiviral agent 74

Antiviral agent 74 是一种抗病毒剂，由 Cidofovir (HY-17438) 前药和脂质链连接组成。Antiviral agent 74 在转化为 Cidofovir 后，能够抑制病毒 DNA 聚合酶的活性。Antiviral agent 74 对牛痘病毒 (VACV) 展现出强大的抗病毒活性 (EC50 值为 0.156 μM)，活性与 Brincidofovir (HY-14532) 相当。Antiviral agent 74 对猴痘病毒 (MPXV) 的效力更强，EC50 值为 0.202 μM。Antiviral agent 74 可用于病毒感染的研究。

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Antiviral agent 74

Antiviral agent 74 Chemical Structure

CAS No. : 3059641-72-1

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Antiviral agent 74 相关抗体

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生物活性

Antiviral agent 74 is an antiviral agent consisting of Cidofovir (HY-17438) prodrug and lipid chain. Antiviral agent 74 can inhibit the activity of viral DNA polymerase by transforming into Cidofovir.Antiviral agent 74 demonstrates potent antiviral activity against vacciniavirus (VACV) (EC50 = 0.156 μM) comparable to Brincidofovir (HY-14532). Antiviral agent 74 shows superior potency against monkeypox virus (MPXV) with an EC50 vales of 0.202 μM. Antiviral agent 74 can be used for the research of virus infection[1].

体外研究
(In Vitro)

Antiviral agent 74 (Compound 13f) 在 Vero 细胞中对牛痘病毒 (VACV) 和猴痘病毒 (MPXV) 显出强效的抗病毒活性，其 EC50 值为 0.156 和 0.202 μM[1]。
Antiviral agent 74 在 Vero 细胞中表现出低细胞，CC50 值为 11.36 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antiviral agent 74 相关抗体:
分子量

623.78

Formula

C28H54N3O8PS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiviral agent 74 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Antiviral agent 743059641-72-1Antiviral agent74Antiviral agent-74OrthopoxvirusDNA/RNA SynthesisVeroVACVMPXVInhibitorinhibitorinhibit

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目录号：
HY-179638
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