2. Apoptosis
  3. Apoptosis
  4. Apoptosis inducer 60

Apoptosis inducer 60 (Compound 4a) 是一种凋亡 (Apoptosis) 诱导剂。Apoptosis inducer 60 可诱导细胞发生浓度依赖性凋亡。Apoptosis inducer 60 对乳腺癌细胞系表现出中等细胞毒性。

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Apoptosis inducer 60

Apoptosis inducer 60 Chemical Structure

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Apoptosis inducer 60 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Apoptosis inducer 60 (Compound 4a) is an Apoptosis inducer. Apoptosis inducer 60 induces concentration-dependent apoptosis in cells. Apoptosis inducer 60 exhibits moderate cytotoxicity against breast cancer cell lines[1].

体外研究
(In Vitro)

Apoptosis inducer 60 (24 h) 可抑制乳腺癌 MCF-7 细胞的活力，其 IC50 为 8.27 μM[1]。
Apoptosis inducer 60 (8.27-16.54 μM; 24 h) 可诱导乳腺癌 MCF-7 细胞发生浓度依赖性凋亡[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis inducer 60 相关抗体:

Apoptosis Analysis[1]

Cell Line: human breast cancer MCF-7 cells
Concentration: 8.27 μM (1× IC50); 16.54 μM (2× IC50)
Incubation Time: 24 h
Result: Increased total apoptosis (early + late) to 16.45% (2.95% early apoptosis, 11.9% late apoptosis, 0.4% necrosis) at 8.27 μM.
Increased total apoptosis to 20.35% (8.65% early apoptosis, 11.7% late apoptosis, 0.9% necrosis) at 16.54 μM.
Showed a concentration-dependent decrease in cell density via microscopic observation.
分子量

1017.12

Formula

C64H56O12
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Apoptosis inducer 60 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apoptosis inducer 60Apoptosis inducer60Apoptosis inducer-60Apoptosisbreast cancerNIH-3T3 cellsMCF-7 breast cancer cellsEGFRapoptotic cell deathMDA-MB-231 human breast cancer cellsbreast cancer cell linesInhibitorinhibitorinhibit

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