2. Protein Tyrosine Kinase/RTK
  3. DYRK
  4. Atalaphyllidine

Atalaphyllidine 是一种天然产物。Atalaphyllidine 可从 Glycosmis chlorosperma 的茎皮中分离得到。Atalaphyllidine 能够抑制 DYRK1A 激酶活性，其 IC50 为 2.2 μM。Atalaphyllidine 可用于神经退行性疾病研究。

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Atalaphyllidine

Atalaphyllidine Chemical Structure

CAS No. : 57959-88-3

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Atalaphyllidine 相关抗体

Top Publications Citing Use of Products

查看 DYRK 亚型特异性产品:

查看所有亚型
DYRK1 DYRK2 DYRK3 DYRK4 HIPK PRP4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Atalaphyllidine is a natural product. Atalaphyllidine can be isolated from the stem bark of Glycosmis chlorosperma. Atalaphyllidine inhibits DYRK1A kinase activity with an IC50 of 2.2 μM. Atalaphyllidine can be used in the research of neurodegenerative diseases[1].

IC50 & Target[1]

DYRK1A

2.2 μM (IC50)

体外研究
(In Vitro)

Atalaphyllidine (30 min) 可抑制 DYRK1A 激酶活性，其 IC50 为 2.2 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Atalaphyllidine 相关抗体:
分子量

309.32

Formula

C18H15NO4
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Atalaphyllidine 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atalaphyllidine57959-88-3DYRKDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinasemouse CLK1down syndromehuman DYRK1AGlu239ATP binding domainratneurodegenerative diseasesLeu241Ile165DYRK1AInhibitorinhibitorinhibit

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目录号：
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