2. Others GPCR/G Protein Neuronal Signaling
  3. Reference Standards mGluR
  4. AZD-8529 mesylate (Standard)

AZD-8529 mesylate (Standard) 是 AZD-8529 (mesylate) (HY-107457A) 的分析标准品。本产品用于研究及分析应用。AZD-8529 mesylate 是一种有效的，高度选择性的，可口服的 mGluR2 正向调节剂，EC50 值为 285 nM；在 20-25 M 的浓度范围内，对 mGluR1，3，4，5，6，7 和 8 没有正向调节作用。

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AZD-8529 mesylate (Standard)

AZD-8529 mesylate (Standard) Chemical Structure

CAS No. : 1314217-69-0

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AZD-8529 mesylate (Standard) 相关抗体

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生物活性

AZD-8529 mesylate (Standard) is the analytical standard of AZD-8529 (mesylate) (HY-107457A). This product is intended for research and analytical applications. AZD-8529 mesylate is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes[1].

IC50 & Target

EC50: 285 nM (mGluR2)[1]
分子量

583.58

Formula

C25H28F3N5O6S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AZD-8529 mesylate (Standard) 相关分类

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Keywords:

AZD-8529 mesylate (Standard)1314217-69-0Reference StandardsmGluRMetabotropic glutamate receptorsmGluR2receptornicotineaddictiontreatmentInhibitorinhibitorinhibit

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