2. Anti-infection
  3. Antibiotic Bacterial
  4. B26 peptoid

B26 peptoid 是一种类肽抗生素 (antibiotic)。B26 peptoid 对一系列革兰氏阳性和革兰氏阴性菌株表现出优异的广谱活性和高选择性。B26 peptoid 可破坏细菌细胞膜并具有杀菌活性。B26 peptoid 诱导细菌产生耐药性的倾向较低。B26 peptoid 可用于细菌感染的相关研究。

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Custom Peptide Synthesis

B26 peptoid

B26 peptoid Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

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Customer Review

B26 peptoid 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

B26 peptoid is a ptoid antibiotic. B26 peptoid exhibits excellent broad-spectrum activity and high selectivity toward a panel of Gram-positive and Gram-negative bacterial strains. B26 peptoid disrupts bacterial membranes and has bactericidal activity. B26 peptoid shows low propensity for bacterial drug resistance. B26 peptoid can be used for the research of bacterial infection[1].

体外研究
(In Vitro)

B26 peptoid (16 h) 可强效抑制耐万古霉素粪肠球菌 (E. faecalis)、耐甲氧西林金黄色葡萄球菌 (S. aureus)、耐甲氧西林表皮葡萄球菌 (S. epidermidis)、大肠杆菌 (E. coli)、铜绿假单胞菌 (P. aeruginosa) 和肺炎克雷伯菌 (K. pneumoniae) 的生长，其 MIC 值范围为 <3 μg/mL[1]。
B26 peptoid (2× MIC; 2 h) 可破坏耐甲氧西林金黄色葡萄球菌和大肠杆菌的细胞膜，使碘化丙啶进入并染色细菌细胞[1]。
B26 peptoid (2× MIC; 2 h) 会对耐甲氧西林金黄色葡萄球菌和大肠杆菌造成严重的膜破坏与细胞损伤，该结果已通过透射电子显微镜观察得到证实[1]。
B26 peptoid 对耐甲氧西林金黄色葡萄球菌在 14 代连续传代过程中保持稳定、一致的抗菌活性，未出现显著的细菌耐药性发展[1]。
B26 peptoid (12 μg/mL; 0-2 h) 可快速杀灭耐甲氧西林金黄色葡萄球菌和大肠杆菌[1]。
B26 peptoid (1 h) 对人红细胞的溶血毒性较低[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

B26 peptoid 相关抗体:

Cell Viability AssayWestern Blot AnalysisCell Proliferation AssayApoptosis AnalysisCell Cytotoxicity AssayCell Cycle AnalysisRT-PCRCell Autophagy AssayImmunofluorescenceCell Differentiation AssayCell Invasion AssayCell Migration Assay Real Time qPCRELISA Assay[1]

Cell Line: methicillin-resistant S. aureus; E. col
Concentration: 12 μg/mL
Incubation Time: 0-2 h
Result: Killed methicillin-resistant S. aureus within 2 hours and E. coli within 1 hour
分子量

1107.60

Formula

C58H114N12O8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

B26 peptoid 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

B26 peptoidAntibioticBacterialGram-positive bacteriamethicillin-resistant S. aureusK. pneumoniaelipid bilayersGram-negative bacteriaE. colimethicillin-resistant S. epidermidisMRSAvancomycin-resistant E. faecalisP. aeruginosaInhibitorinhibitorinhibit

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目录号：
HY-P11659
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