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  4. Tetrakis(hydroxymethyl)phosphonium sulfate

Tetrakis(hydroxymethyl)phosphonium sulfate 是一种蛋白质交联剂及水凝胶调节剂。Tetrakis(hydroxymethyl)phosphonium sulfate 能够通过曼尼希型反应与氨基酸或蛋白质的伯胺及仲胺发生共价结合，从而在蛋白质分子间构建稳定的交联键。Tetrakis(hydroxymethyl)phosphonium sulfate 不仅能调节重组弹性蛋白样蛋白水凝胶的凝胶化时间和储能模量，还表现出良好的细胞相容性，能够支持三维包埋环境下的胚胎干细胞和神经细胞的分化与生长。Tetrakis(hydroxymethyl)phosphonium sulfate 适用于基于蛋白质的水凝胶体系，特别是细胞包埋相关的应用。

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Tetrakis(hydroxymethyl)phosphonium sulfate

Tetrakis(hydroxymethyl)phosphonium sulfate Chemical Structure

CAS No. : 55566-30-8

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Tetrakis(hydroxymethyl)phosphonium sulfate 相关抗体

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生物活性

Tetrakis (hydroxymethyl) phosphonium sulfate is a protein crosslinker and hydrogel modifier. Tetrakis (hydroxymethyl) phosphonium sulfate covalently binds to primary and secondary amines of amino acids or proteins via a Mannich-type reaction, thereby constructing stable crosslinking bonds between protein molecules. Tetrakis (hydroxymethyl) phosphonium sulfate not only regulates the gelation time and storage modulus of recombinant elastin-like protein hydrogels, but also exhibits excellent cytocompatibility, and supports the differentiation and growth of embryonic stem cells and neural cells in a three-dimensional encapsulation environment. Tetrakis (hydroxymethyl) phosphonium sulfate is suitable for protein-based hydrogel systems, especially for applications related to cell encapsulation[1].

分子量

406.28

Formula

C4H12O4P·1/2SO4
CAS 号
性状

液体

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料
参考文献

Tetrakis(hydroxymethyl)phosphonium sulfate 相关分类

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Keywords:

Tetrakis(hydroxymethyl)phosphonium55566-30-8Biochemical Assay Reagentsamino acidsMannich-type reactionprotein crosslinkerproteinsrecombinant elastin-like protein hydrogelsneuronal cellshydrogel modulatorprimary aminessecondary aminesembryonic stem cellsInhibitorinhibitorinhibit

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