2. 天然产物
  3. 植物 黄酮类
  4. 芸香科 二氢黄酮
  5. 柠檬
  6. Brutieridin

Brutieridin (Compound 1) 是一种黄烷酮苷类化合物，可以从香柠檬 (佛手柑 Citrus bergamia) 的果汁中分离得到。Brutieridin 可降低肠道上皮细胞中的 NPC1L1 水平。Brutieridin 可减少肠道上皮细胞的胆固醇摄取。Brutieridin 可用于高胆固醇血症的研究。

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Brutieridin

Brutieridin Chemical Structure

CAS No. : 1162664-57-4

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Brutieridin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Brutieridin (Compound 1) is a flavanone glycoside that can be isolated from the juice of bergamot (Citrus bergamia). Brutieridin reduces the level of NPC1L1 in intestinal epithelial cells. Brutieridin decreases cholesterol uptake by intestinal epithelial cells. Brutieridin can be used in the research of hypercholesterolemia[1][2].

体外研究
(In Vitro)

Brutieridin (100 μM; 24 h) 可显著抑制 Caco-2 细胞中的胆固醇摄取[2]。
Brutieridin (100 μM; 24 h) 可在孵育 24 h 后使 Caco-2 细胞中的 NPC1L1 蛋白表达降低近 50%[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Brutieridin 相关抗体:

Western Blot Analysis[2]

Cell Line: Caco-2 human epithelial colorectal adenocarcinoma cells
Concentration: 100 μM
Incubation Time: 24 h
Result: Induced a nearly 50% reduction of NPC1L1 protein expression compared to the control group, with a statistically significant difference.
分子量

754.69

Formula

C34H42O19
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Brutieridin 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Brutieridin1162664-57-4Othersflavanone glycosideCaco-2 cellshypercholesterolemiaInhibitorinhibitorinhibit

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