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  3. Chingchengenamide A

Chingchengenamide A 是一种天然的生物碱。

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Chingchengenamide A

Chingchengenamide A Chemical Structure

CAS No. : 139906-29-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chingchengenamide A is a natural alkaloid.

体外研究
(In Vitro)

Chingchengenamide A (100 μg;24 h) 对受试的革兰氏阳性菌和革兰氏阴性菌均表现出抗菌活性,其中对 Pseudomonas aeruginosa 的抑菌圈直径最大 (21 mm)[1]
Chingchengenamide A 具有良好的 ADMET 特性,包括高人体肠道吸收率、良好的 Caco-2 通透性以及无致癌性[1]
Chingchengenamide A (0.1-100 μM;90 min) 胡增加 Caco-2 细胞的葡萄糖摄取,但不会影响其脂肪酸摄取[2]
Chingchengenamide A (0.00125-0.01 mg/mL;48 h) 对白纹伊蚊 (Aedes albopictus) 三龄幼虫具有强效杀灭作[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Chingchengenamide A (10-20 mg/kg;p.o.) 在瑞士白化小鼠 (Castor oil (HY-107799) 诱导腹泻模型) 中表现出剂量依赖性的止泻活性[1]
Chingchengenamide A (10-20 mg/kg;p.o.) 在瑞士白化小鼠 (Acetic acid (HY-Y0319) 诱导扭体模型) 中表现出剂量依赖性镇痛活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Swiss albino mice induced by Castor oil (4–5 weeks old, both genders)[1]
Dosage: 10 mg/kg; 20 mg/kg
Administration: p.o.
Result: Reduced diarrhea by 33.33% at 10 mg/kg; reduced diarrhea by 40% at 20 mg/kg.
Animal Model: Swiss albino mice induced by Acetic acid (4–5 weeks old, both genders)[1]
Dosage: 10 mg/kg; 20 mg/kg
Administration: p.o.
Result: Reduced writhing by 34.69% at 10 mg/kg; reduced writhing by 42.86% at 20 mg/kg.
分子量

301.38

Formula

C18H23NO3

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Chingchengenamide A
目录号:
HY-N16926
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