2. Neuronal Signaling GPCR/G Protein Immunology/Inflammation
  3. Amyloid-β α-synuclein Amylin Receptor Tau Protein SOD
  4. CLR01 sodium

CLR01 sodium 是一种可透过血脑屏障的抗聚集剂。CLR01 sodium 可抑制 Amyloid-β 40/42、α-synuclein、IAPP、tau 蛋白及 SOD1 的新生聚集。CLR01 sodium 可降低三转基因小鼠皮层中的淀粉样斑块负荷，并改善这些小鼠的记忆与运动能力。CLR01 sodium 可用于阿尔茨海默病、帕金森病、肌萎缩侧索硬化症 (ALS) 的相关研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

CLR01 sodium

CLR01 sodium Chemical Structure

CAS No. : 1338489-62-5

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

CLR01 sodium 相关抗体

Top Publications Citing Use of Products

查看 α-synuclein 亚型特异性产品:

查看所有亚型
α-synuclein α-synuclein Aggregation α-synuclein/CHMP2B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CLR01 sodium is a blood-brain barrier-permeable anti-aggregation agent. CLR01 sodium inhibits the de novo aggregation of Amyloid-β 40/42, α-synuclein, IAPP, tau protein and SOD1. CLR01 sodium reduces amyloid plaque burden in the cortex of triple-transgenic mice and improves the memory and motor abilities of these mice. CLR01 sodium can be used in research related to Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS)[1].

体外研究
(In Vitro)

CLR01 可在 PBS 缓冲液中以 10 μM 的 Kd 结合 KLVFF 肽的 N 端赖氨酸[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CLR01 sodium 相关抗体:
体内研究
(In Vivo)

CLR01 (每日 40 μg/kg) 可降低三重转基因阿尔茨海默病小鼠的皮质斑块负荷，并改善其记忆与运动能力[1]。
CLR01 可显著降低 G93A-SOD1 肌萎缩侧索硬化 (ALS) 小鼠脊髓中错误折叠的 SOD1 蛋白水平，但在该快速进展模型中无法改善其运动功能[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

770.61

Formula

C42H30Na2O8P2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CLR01 sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CLR011338489-62-5CLR 01CLR-01Amyloid-βα-synucleinAmylin ReceptorTau ProteinSODβ-amyloid peptideAβAbetaα-SynAMYRSuperoxide DismutaseSOD1mice14-3-3 proteinG93A-SOD1 mouse modelstriply transgenic miceLys-214 residueIAPPtauamyloid-β 40/42Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
CLR01 sodium
目录号：
HY-182304
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z