2. Immunology/Inflammation Neuronal Signaling Membrane Transporter/Ion Channel Others
  3. Complement System Calcium Channel Drug Derivative
  4. [DArg10, DAla20] TLQP-21

[DArg10, DAla20] TLQP-21，即 TLQP-21 (HY-P1345) 类似物，是一种 C3aR 激动剂 (对于 β-arrestin 募集的 EC50：为 87 nM)。[DArg10, DAla20] TLQP-21 可诱导钙离子内流 (calcium influx)。[DArg10, DAla20] TLQP-21 可轻微但不显著地增强肾上腺素能诱导的脂肪分解。[DArg10, DAla20] TLQP-21 可用于炎症性疾病、代谢紊乱和神经系统疾病研究。

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Custom Peptide Synthesis

[DArg10, DAla20] TLQP-21

[DArg10, DAla20] TLQP-21 Chemical Structure

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Other Forms of [DArg10, DAla20] TLQP-21:

[DArg10, DAla20] TLQP-21 相关抗体

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[DArg10, DAla20] TLQP-21, TLQP-21 (HY-P1345) analogue, is a C3aR agonist (EC50: 87 nM for β-arrestin recruitment). [DArg10, DAla20] TLQP-21 elicits calcium influx. [DArg10, DAla20] TLQP-21 slightly but not significantly potentiates adrenergic-induced lipolysis. [DArg10, DAla20] TLQP-21 can be used in the research of inflammatory diseases, metabolic disorders, and neurological conditions[1].

分子量

2432.75

Formula

C107H170N40O26
Sequence

Thr-Leu-Gln-Pro-Pro-Ala-Ser-Ser-Arg-{d-Arg}-Arg-His-Phe-His-His-Ala-Leu-Pro-Pro-{d-Ala}-Arg
Sequence Shortening

TLQPPASSR-{d-Arg}-RHFHHALPP-{d-Ala}-R
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

[DArg10, DAla20] TLQP-21 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[DArg10, DAla20] TLQP-21Complement SystemCalcium ChannelDrug DerivativeCa2+ channelsCa channelsDrug derivativeInhibitorinhibitorinhibit

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产品名称：
[DArg10, DAla20] TLQP-21
目录号：
HY-P1345B
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